Alexander V Bocharov
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Explore the profile of Alexander V Bocharov including associated specialties, affiliations and a list of published articles.
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29
Citations
874
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Recent Articles
1.
Chen Z, Eggerman T, Bocharov A, Baranova I, Vishnyakova T, Patterson A
J Virol
. 2025 Jan;
99(2):e0187924.
PMID: 39868801
Importance: As human host restriction factors, A3s play an important role against viral infections. A3s are also major mutagenic drivers of cancer. However, why A3-induced mutations vary significantly from non-lethal...
2.
Baranova I, Bocharov A, Vishnyakova T, Chen Z, Ke Y, Birukova A, et al.
Cells
. 2024 Dec;
13(23).
PMID: 39682740
The class B scavenger receptor CD36 is known to bind and mediate the transport of lipid-related ligands and it functions as a pattern recognition receptor (PRR) for a variety of...
3.
Karki P, Li Y, Zhang C, Ke Y, Promnares K, Birukova A, et al.
Am J Respir Cell Mol Biol
. 2023 Sep;
70(1):11-25.
PMID: 37725486
The generation of bioactive truncated oxidized phospholipids (Tr-OxPLs) from oxidation of cell-membrane or circulating lipoproteins is a common feature of various pathological states. Scavenger receptor CD36 is involved in lipid...
4.
Sorokin A, Hong C, Aponte A, Florida E, Tang J, Patel N, et al.
JCI Insight
. 2023 Sep;
8(20.
PMID: 37698922
Background: Oxidized apolipoprotein B (oxLDL) and oxidized ApoA-I (oxHDL) are proatherogenic. Their prognostic value for assessing high-risk plaques by coronary computed tomography angiography (CCTA) is missing. Methods: In a prospective,...
5.
Ke Y, Karki P, Li Y, Promnares K, Zhang C, Eggerman T, et al.
Cells
. 2023 Aug;
12(15).
PMID: 37566016
Truncated phospholipid oxidation products (Tr-OxPL) increase in blood circulation with aging; however, their role in the severity of vascular dysfunction and bacterial lung injury in aging groups remains poorly understood....
6.
Uppal S, Postnikova O, Villasmil R, Rogozin I, Bocharov A, Eggerman T, et al.
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511618
Here, we present evidence that caveolae-mediated endocytosis using LDLR is the pathway for SARS-CoV-2 virus internalization in the ocular cell line ARPE-19. Firstly, we found that, while Angiotensin-converting enzyme 2...
7.
Baranova I, Bocharov A, Vishnyakova T, Chen Z, Birukova A, Ke Y, et al.
Infect Immun
. 2022 Sep;
90(10):e0040422.
PMID: 36165628
No abstract available.
8.
Chen Z, Eggerman T, Bocharov A, Baranova I, Vishnyakova T, Patterson A
J Biol Chem
. 2021 Jun;
297(2):100889.
PMID: 34181944
APOBEC3s are innate single-stranded DNA cytidine-to-uridine deaminases that catalyze mutations in both pathogen and human genomes with significant roles in human disease. However, how APOBEC3s mutate a single-stranded DNA that...
9.
Baranova I, Bocharov A, Vishnyakova T, Chen Z, Birukova A, Ke Y, et al.
Infect Immun
. 2021 Jun;
89(10):e0030121.
PMID: 34097506
Recent studies suggest an anti-inflammatory protective role for class B scavenger receptor BI (SR-BI) in endotoxin-induced inflammation and sepsis. Other data, including ours, provide evidence for an alternative role of...
10.
Vishnyakova T, Bocharov A, Baranova I, Kurlander R, Drake S, Chen Z, et al.
PLoS One
. 2020 Oct;
15(10):e0240659.
PMID: 33057430
SR-BI binds various lipoproteins, including HDL, LDL as well as VLDL, and mediates selective cholesteryl ester (CE) uptake. HDL derived CE accumulates in cellular lipid droplets (LDs), which also store...