Alexander T Prechtel
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Explore the profile of Alexander T Prechtel including associated specialties, affiliations and a list of published articles.
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16
Citations
545
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Recent Articles
1.
Siegert I, Schatz V, Prechtel A, Steinkasserer A, Bogdan C, Jantsch J
Methods Mol Biol
. 2014 Feb;
1121:111-9.
PMID: 24510816
Dendritic cells (DC) and macrophages (MΦ) play a pivotal role in antimicrobial defense, in the regulation of immune responses, and in maintaining tissue homeostasis. The analysis of DC and MΦ...
2.
Pieper D, Schirmer S, Prechtel A, Kehlenbach R, Hauber J, Chemnitz J
PLoS One
. 2011 Aug;
6(8):e23290.
PMID: 21829725
Maturation of dendritic cells (DC) is characterized by expression of CD83, a surface protein that appears to be necessary for the effective activation of naïve T-cells and T-helper cells by...
3.
Goldwich A, Prechtel A, Muhl-Zurbes P, Pangratz N, Stossel H, Romani N, et al.
J Leukoc Biol
. 2011 Mar;
89(6):973-9.
PMID: 21427206
HSV-1 is a very successful representative of the α-herpesvirus family, and ∼ 90% of the population is seropositive for this particular virus. Although the pathogen usually causes the well-known mild...
4.
Eisemann J, Prechtel A, Muhl-Zurbes P, Steinkasserer A, Kummer M
Immunobiology
. 2009 Jul;
214(9-10):861-7.
PMID: 19619915
Mature dendritic cells (mDCs) are the most potent antigen presenting cells within the human immune system known today. However, several viruses, including herpes simplex virus type 1 (HSV-1) have developed...
5.
Kummer M, Prechtel A, Muhl-Zurbes P, Turza N, Steinkasserer A
Immunobiology
. 2009 Jul;
214(9-10):852-60.
PMID: 19586683
Dendritic cells are the sentinels of the immune system and as such represent the first-line of defense against incoming pathogens. Upon encounter with harmful antigens, these antigen-presenting cells start to...
6.
Jantsch J, Turza N, Volke M, Eckardt K, Hensel M, Steinkasserer A, et al.
J Immunol Methods
. 2008 Jun;
337(1):71-7.
PMID: 18514219
Selective gene silencing by RNA interference (RNAi) has been shown to be an efficient method for the targeted manipulation of cellular functions. In this study we describe for the first...
7.
Jantsch J, Chakravortty D, Turza N, Prechtel A, Buchholz B, Gerlach R, et al.
J Immunol
. 2008 Mar;
180(7):4697-705.
PMID: 18354193
Dendritic cells (DC) play a key role in linking innate and adaptive immunity. In inflamed tissues, where DC become activated, oxygen tensions are usually low. Although hypoxia is increasingly recognized...
8.
Theodoridis A, Prechtel A, Turza N, Zenke M, Steinkasserer A
Immunobiology
. 2007 Dec;
212(9-10):827-38.
PMID: 18086382
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) of the immune system. Their migration to secondary lymphoid tissues is a crucial step for the priming of T cells...
9.
Prechtel A, Turza N, Theodoridis A, Steinkasserer A
J Immunol
. 2007 Apr;
178(9):5454-64.
PMID: 17442926
Mature human dendritic cells (mDCs) are the most powerful APCs known today, having the unique ability to induce primary immune responses. One of the best known surface markers for mDCs...
10.
Kummer M, Turza N, Muhl-Zurbes P, Lechmann M, Boutell C, Coffin R, et al.
J Virol
. 2007 Apr;
81(12):6326-38.
PMID: 17428858
Mature dendritic cells (DCs) are the most potent antigen-presenting cells within the human immune system. However, Herpes simplex virus type 1 (HSV-1) is able to interfere with DC biology and...