Alexander R Goldberg
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Explore the profile of Alexander R Goldberg including associated specialties, affiliations and a list of published articles.
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9
Citations
522
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Recent Articles
1.
Goldberg A, Dovas A, Torres D, Pereira B, Viswanathan A, Das Sharma S, et al.
Neuron
. 2025 Jan;
PMID: 39837324
Gliomas are aggressive neoplasms that diffusely infiltrate the brain and cause neurological symptoms, including cognitive deficits and seizures. Increased mTOR signaling has been implicated in glioma-induced neuronal hyperexcitability, but the...
2.
Rifkin R, Wu X, Pereira B, Gill B, Merricks E, Michalak A, et al.
Neuropharmacology
. 2024 Dec;
265():110259.
PMID: 39662702
Tumor associated epilepsy is a common and debilitating co-morbidity of brain tumors, for which inadequate treatments are available. Additionally, animal models suggest a potential link between seizures and tumor progression....
3.
Goldberg A, Dovas A, Torres D, Das Sharma S, Mela A, Merricks E, et al.
bioRxiv
. 2024 Jan;
PMID: 38293120
Gliomas are highly aggressive brain tumors characterized by poor prognosis and composed of diffusely infiltrating tumor cells that intermingle with non-neoplastic cells in the tumor microenvironment, including neurons. Neurons are...
4.
Al-Dalahmah O, Argenziano M, Kannan A, Mahajan A, Furnari J, Paryani F, et al.
Nat Commun
. 2023 May;
14(1):2586.
PMID: 37142563
Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain cells, including astrocytes, neurons and microglia/myeloid cells. This complex mixture of cell types forms the biological context for therapeutic...
5.
Gill B, Khan F, Goldberg A, Merricks E, Wu X, Sosunov A, et al.
Brain
. 2022 May;
145(10):3666-3680.
PMID: 35552612
While several studies have attributed the development of tumour-associated seizures to an excitatory-inhibitory imbalance, we have yet to resolve the spatiotemporal interplay between different types of neuron in glioma-infiltrated cortex....
6.
Montgomery M, Kim S, Dovas A, Zhao H, Goldberg A, Xu W, et al.
Cell Rep
. 2020 Apr;
31(2):107500.
PMID: 32294436
Diffusely infiltrating gliomas are known to cause alterations in cortical function, vascular disruption, and seizures. These neurological complications present major clinical challenges, yet their underlying mechanisms and causal relationships to...
7.
Bohm-Levine N, Goldberg A, Mariani M, Frankfurt M, Thornton J
Horm Behav
. 2019 Oct;
118:104590.
PMID: 31593698
Alzheimer's disease and other forms of cognitive decline are significantly more prevalent in post-menopausal women. Decreased estrogen levels, due to menopause or ovariectomy, may contribute to memory impairments and neurodegeneration....
8.
Jimenez J, Su K, Goldberg A, Luna V, Biane J, Ordek G, et al.
Neuron
. 2018 Feb;
97(3):670-683.e6.
PMID: 29397273
The hippocampus is traditionally thought to transmit contextual information to limbic structures where it acquires valence. Using freely moving calcium imaging and optogenetics, we show that while the dorsal CA1...
9.
Danielson N, Kaifosh P, Zaremba J, Lovett-Barron M, Tsai J, Denny C, et al.
Neuron
. 2016 Mar;
90(1):101-12.
PMID: 26971949
Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it remains unknown how these cells behave in vivo. Here, we have used two-photon calcium imaging to monitor...
10.
Goldberg A, Northrop B
J Org Chem
. 2016 Jan;
81(3):969-80.
PMID: 26734844
The solution phase self-assembly of boronate esters, diazaboroles, oxathiaboroles, and dithiaboroles from the condensation of arylboronic acids with aromatic diol, diamine, hydroxythiol, and dithiol compounds in chloroform has been investigated...