Alexander R Ball Jr
Overview
Explore the profile of Alexander R Ball Jr including associated specialties, affiliations and a list of published articles.
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18
Citations
691
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Recent Articles
1.
Ayoubi R, Ryan J, Gonzalez Bolivar S, Alende C, Ruiz Moleon V, Fotouhi M, et al.
Nat Protoc
. 2024 Dec;
PMID: 39690206
Antibody-based research applications are critical for biological discovery. Yet there are no industry standards for comparing the performance of antibodies in various applications. We describe a knockout cell line-based antibody...
2.
Kong X, Ball Jr A, Yokomori K
Methods Mol Biol
. 2016 Nov;
1515:227-242.
PMID: 27797083
In addition to their mitotic and transcriptional functions, cohesin plays critical roles in DNA damage response (DDR) and repair. Specifically, cohesin promotes homologous recombination (HR) repair of DNA double-strand breaks...
3.
Zeng W, Jiang S, Kong X, El-Ali N, Ball Jr A, Ma C, et al.
Nucleic Acids Res
. 2016 Aug;
44(21):e158.
PMID: 27566152
Myoblasts are precursor skeletal muscle cells that differentiate into fused, multinucleated myotubes. Current single-cell microfluidic methods are not optimized for capturing very large, multinucleated cells such as myotubes. To circumvent...
4.
Zeng W, Chen Y, Newkirk D, Wu B, Balog J, Kong X, et al.
Hum Mutat
. 2014 May;
35(8):998-1010.
PMID: 24838473
Facioscapulohumeral dystrophy (FSHD) is one of the most prevalent muscular dystrophies. The majority of FSHD cases are linked to a decreased copy number of D4Z4 macrosatellite repeats on chromosome 4q...
5.
Kong X, Ball Jr A, Pham H, Zeng W, Chen H, Schmiesing J, et al.
Mol Cell Biol
. 2013 Dec;
34(4):685-98.
PMID: 24324008
Cohesin is an essential multiprotein complex that mediates sister chromatid cohesion critical for proper segregation of chromosomes during cell division. Cohesin is also involved in DNA double-strand break (DSB) repair....
6.
Ball Jr A, Chen Y, Yokomori K
Biochim Biophys Acta
. 2013 Nov;
1839(3):191-202.
PMID: 24269489
Cohesins are conserved and essential Structural Maintenance of Chromosomes (SMC) protein-containing complexes that physically interact with chromatin and modulate higher-order chromatin organization. Cohesins mediate sister chromatid cohesion and cellular long-distance...
7.
Kong X, Stephens J, Ball Jr A, Heale J, Newkirk D, Berns M, et al.
PLoS One
. 2011 Aug;
6(8):e23548.
PMID: 21858164
Condensin I is important for chromosome organization and segregation in mitosis. We previously showed that condensin I also interacts with PARP1 in response to DNA damage and plays a role...
8.
Ball Jr A, Yokomori K
Curr Opin Cell Biol
. 2011 Apr;
23(3):277-83.
PMID: 21489773
Technical advances in recent years, such as laser microirradiation and chromatin immunoprecipitation, have led to further understanding of DNA damage responses and repair processes as they happen in vivo and...
9.
Chien R, Zeng W, Kawauchi S, Bender M, Santos R, Gregson H, et al.
J Biol Chem
. 2011 Apr;
286(20):17870-8.
PMID: 21454523
The β-globin locus undergoes dynamic chromatin interaction changes in differentiating erythroid cells that are thought to be important for proper globin gene expression. However, the underlying mechanisms are unclear. The...
10.
Zeng W, Ball Jr A, Yokomori K
Epigenetics
. 2010 Apr;
5(4):287-92.
PMID: 20421743
Heterochromatin Protein 1 (HP1) is a transcriptional repressor that directly binds to the methylated lysine 9 residue of histone H3 (H3K9me), which is a hallmark histone modification for transcriptionally silenced...