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Alexander Kreymerman

Explore the profile of Alexander Kreymerman including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 392
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Recent Articles
1.
Belle K, Kreymerman A, Young J, Vadgama N, Ji M, Randhawa S, et al.
Mol Genet Metab . 2025 Feb; 144(3):109049. PMID: 39986240
No abstract available.
2.
Velayutham N, Garbern J, Elwell H, Zhuo Z, Ruland L, Elcure Alvarez F, et al.
J Am Heart Assoc . 2024 Jun; 13(13):e033155. PMID: 38934864
Background: Current protocols generate highly pure human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in vitro that recapitulate characteristics of mature in vivo cardiomyocytes. Yet, a risk of arrhythmias exists when...
3.
Belle K, Kreymerman A, Vadgama N, Ji M, Randhawa S, Caicedo J, et al.
medRxiv . 2023 Nov; PMID: 37961166
Patients with mitochondrial disorders present with clinically diverse symptoms, largely driven by heterogeneous mutations in mitochondrial-encoded and nuclear-encoded mitochondrial genes. These mutations ultimately lead to complex biochemical disorders with a...
4.
Guilbaud A, Ghanegolmohammadi F, Wang Y, Leng J, Kreymerman A, Gamboa Varela J, et al.
Nucleic Acids Res . 2023 Oct; 51(20):10829-10845. PMID: 37843128
DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass...
5.
Paul K, Krolewski R, Lucumi Moreno E, Blank J, Holton K, Ahfeldt T, et al.
Nat Commun . 2023 Jun; 14(1):3747. PMID: 37353544
No abstract available.
6.
Paul K, Krolewski R, Lucumi Moreno E, Blank J, Holton K, Ahfeldt T, et al.
Nat Commun . 2023 May; 14(1):2803. PMID: 37193692
Parkinson's disease (PD) is a complex neurodegenerative disease with etiology rooted in genetic vulnerability and environmental factors. Here we combine quantitative epidemiologic study of pesticide exposures and PD with toxicity...
7.
Wood E, Kreymerman A, Kowal T, Buickians D, Sun Y, Muscat S, et al.
Prog Retin Eye Res . 2022 Dec; 96:101153. PMID: 36503723
Optogenetics is defined as the combination of genetic and optical methods to induce or inhibit well-defined events in isolated cells, tissues, or animals. While optogenetics within ophthalmology has been primarily...
8.
Vadgama N, Kreymerman A, Campbell J, Shamardina O, Brugger C, Consortium G, et al.
Front Genet . 2022 May; 13:888025. PMID: 35571054
There is considerable variability in the susceptibility and progression for COVID-19 and it appears to be strongly correlated with age, gender, ethnicity and pre-existing health conditions. However, to our knowledge,...
9.
Ji M, Kreymerman A, Belle K, Ghiam B, Muscat S, Mahajan V, et al.
Transl Vis Sci Technol . 2021 Jul; 10(8):4. PMID: 34232272
Mitochondria are viable therapeutic targets for a broad spectrum of ocular diseases.
10.
Chang K, Bian M, Xia X, Madaan A, Sun C, Wang Q, et al.
eNeuro . 2021 Jan; 8(1). PMID: 33441400
The failure of adult CNS neurons to survive and regenerate their axons after injury or in neurodegenerative disease remains a major target for basic and clinical neuroscience. Recent data demonstrated...