Alexander J Szalai
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Explore the profile of Alexander J Szalai including associated specialties, affiliations and a list of published articles.
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68
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1931
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Recent Articles
1.
Ziemanski J, Szalai A
Cornea
. 2023 Nov;
43(3):365-371.
PMID: 37983311
Purpose: The aim of this study was to assess whether complement proteins C3 and C4 are produced by immortalized human conjunctival epithelial (HCjE) cells. Methods: Supernatants and cell lysates from...
2.
Alduraibi F, Saleem M, Ricart K, Patel R, Szalai A, Singh J
J Rheumatol
. 2022 Dec;
50(6):817-826.
PMID: 36521917
Objective: This single-center clinical study identifies clusters of different phenotypes and pathophysiology subtypes of patients with gout and associated comorbidities. Methods: Patients clinically diagnosed with gout were enrolled between January...
3.
Sharma V, Pope B, Santiago N, Boland M, Sun D, Reynolds R, et al.
ACR Open Rheumatol
. 2021 Mar;
3(4):277-283.
PMID: 33779079
Objective: We investigated whether a previously reported association of IFNGR expression with rheumatoid arthritis (RA) and its radiographic severity reflects differences in proximal interferon-γ (IFN-γ) signaling in T cells from...
4.
Jimenez R, Szalai A
Front Immunol
. 2021 Feb;
11:619564.
PMID: 33633738
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated...
5.
Avery J, Jimenez R, Blake J, Wright T, Leon-Ruiz B, Schoeb T, et al.
Mamm Genome
. 2019 Nov;
30(9-10):245-259.
PMID: 31673770
Genome-wide association studies (GWAS) and functional genomic analyses have implicated several ITGAM (CD11b) single-nucleotide polymorphisms (SNPs) in the development of SLE and other disorders. ITGAM encodes the α chain of...
6.
Jimenez R, Kuznetsova V, Connelly A, Hel Z, Szalai A
Front Immunol
. 2019 Oct;
10:2183.
PMID: 31620123
Previously we established that human C-reactive protein (CRP) exacerbates mouse acute kidney injury and that the effect was associated with heightened renal accumulation of myeloid derived cells with suppressor functions...
7.
Jimenez R, Wright T, Jones N, Wu J, Gibson A, Szalai A
Front Immunol
. 2018 Mar;
9:372.
PMID: 29556231
C-reactive protein (CRP) is the prototypical acute phase reactant, increasing in blood concentration rapidly and several-fold in response to inflammation. Recent evidence indicates that CRP has an important physiological role...
8.
Tanigaki K, Sacharidou A, Peng J, Chambliss K, Yuhanna I, Ghosh D, et al.
J Clin Invest
. 2017 Dec;
128(1):309-322.
PMID: 29202472
Type 2 diabetes mellitus (T2DM) is a common complication of obesity. Here, we have shown that activation of the IgG receptor FcγRIIB in endothelium by hyposialylated IgG plays an important...
9.
Lai W, Tang Y, Huang X, Tang P, Xu A, Szalai A, et al.
Kidney Int
. 2016 Jul;
90(3):610-26.
PMID: 27470679
Acute kidney injury (AKI) is exacerbated in C-reactive protein transgenic mice but alleviated in Smad3 knockout mice. Here we used C-reactive protein transgenic/Smad3 wild-type and C-reactive protein transgenic/Smad3 knockout mice...
10.
Pegues M, McWilliams I, Szalai A
Am J Physiol Renal Physiol
. 2016 Apr;
311(1):F176-81.
PMID: 27053688
Myeloid-derived suppressor cells (MDSCs) are a CD11b(+)Gr1(+) population in mice that can be separated into granulocytic (g-MDSC) and monocytic (m-MDSC) subtypes based on their expression of Ly6G and Ly6C. Both...