Alexander J Szalai
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Explore the profile of Alexander J Szalai including associated specialties, affiliations and a list of published articles.
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68
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1931
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Recent Articles
11.
Li J, Wei D, McCrory M, Szalai A, Yang G, Li L, et al.
Biochem J
. 2016 Mar;
473(9):1215-24.
PMID: 26933237
Defective central leptin signalling and impaired leptin entry into the CNS (central nervous system) represent two important aspects of leptin resistance in obesity. In the present study, we tested whether...
12.
Wright T, Jimenez R, Morgan T, Bali N, Hou X, McCrory M, et al.
Autoimmune Dis
. 2015 Oct;
2015:640171.
PMID: 26421184
We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). The...
13.
Powell M, Pegues M, Szalai A, Ghanta V, DAbramo L, Watts S
Comp Med
. 2015 Aug;
65(4):289-94.
PMID: 26310458
The diets of populations in industrialized nations have shifted to dramatically increased consumption of ω6 polyunsaturated fatty acids (PUFA), with a corresponding decrease in the consumption of ω3 PUFA. This...
14.
Zhang L, Liu S, Wright T, Shen Z, Li H, Zhu W, et al.
J Immunol
. 2015 Apr;
194(11):5243-52.
PMID: 25917100
Human C-reactive protein (CRP) is a serum-soluble pattern recognition receptor that serves as a marker of inflammation and directly contributes to innate immunity. In this study, we show that human...
15.
Zhou Y, Kucik D, Szalai A, Edberg J
J Vis Exp
. 2014 Jul;
(89).
PMID: 25045887
Neutrophil firm adhesion to endothelial cells plays a critical role in inflammation in both health and disease. The process of neutrophil firm adhesion involves many different adhesion molecules including members...
16.
Szalai A, Barnum S, Ramos T
Trans R Soc Trop Med Hyg
. 2014 Jul;
108(9):591-3.
PMID: 25002461
Background: C-reactive protein (CRP) level correlates with parasitemia and severity of malaria, but whether this reflects causality remains unknown. Methods: Using CRP-transgenic and CRP-deficient mice we compared the onset and...
17.
Bowling M, Xing D, Kapadia A, Chen Y, Szalai A, Oparil S, et al.
Arterioscler Thromb Vasc Biol
. 2014 May;
34(7):1477-1485.
PMID: 24876352
Objective: 17β-Estradiol (E2) offers cardiovascular protection in young female animals and postmenopausal women. In contrast, randomized trials of menopausal hormones performed in older women have shown harm or no cardiovascular...
18.
Owsley C, Huisingh C, Jackson G, Curcio C, Szalai A, Dashti N, et al.
Invest Ophthalmol Vis Sci
. 2014 May;
55(8):4776-89.
PMID: 24854857
Purpose: Delayed rod-mediated dark adaptation (DA) is characteristic of early age-related macular degeneration (AMD) and also can be observed in some older adults in normal macular health. We examine cross-sectional...
19.
Szalai A, McCrory M, Xing D, Hage F, Miller A, Oparil S, et al.
Mediators Inflamm
. 2014 May;
2014:353614.
PMID: 24803739
Raised blood C-reactive protein (CRP) level is a predictor of cardiovascular events, but whether blood CRP is causal in the disease process is unknown. The latter would best be defined...
20.
Tang Y, Huang X, Lv J, Chung A, Zhang Y, Chen J, et al.
Clin Sci (Lond)
. 2013 Nov;
126(9):645-59.
PMID: 24206243
CRP (C-reactive protein) is regarded as an inflammatory biomarker in AKI (acute kidney injury), but its exact role in AKI remains unclear. Thus we sought to investigate the role of...