Alexander Hoffmann
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Explore the profile of Alexander Hoffmann including associated specialties, affiliations and a list of published articles.
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261
Citations
9693
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Recent Articles
1.
Pape D, Bertemes B, Dinis C, Dessard J, Gryson T, Fonteyn Y, et al.
Orthopadie (Heidelb)
. 2025 Feb;
PMID: 39992368
Background: The frequent use of magnetic resonance imaging (MRI) introduced "bone marrow edema" (BME) as a descriptive radiological term for hyperintense signal changes in fluid-sensitive sequences. With the optimization of...
2.
Nakamura E, Blanchini F, Giordano G, Hoffmann A, Franco E
bioRxiv
. 2025 Feb;
PMID: 39990486
Cells have the capacity to encode and decode information in the temporal features of molecular signals. Many pathways, for example, generate either sustained or pulsatile responses depending on the context,...
3.
Schiffman A, Cheng Z, Ourthiague D, Hoffmann A
bioRxiv
. 2025 Feb;
PMID: 39975349
Type I interferon IFNβ is a key regulator of the immune response, and its dysregulated expression causes disease. The regulation of IFNβ promoter activity has been a touchpoint of mammalian...
4.
Wang A, Son M, Gorin A, Kenna E, Padhi A, Keisham B, et al.
Cell Syst
. 2025 Feb;
16(2):101171.
PMID: 39938520
Cells of the immune system operate in dynamic microenvironments where the timing, concentration, and order of signaling molecules constantly change. Despite this complexity, immune cells manage to communicate accurately and...
5.
Navarro H, Daly A, Rodriguez B, Wu S, Ngo K, Fraser A, et al.
Cell Discov
. 2025 Feb;
11(1):13.
PMID: 39929805
A group of autoinflammatory disorders termed relopathies arise as a consequence of NF-κB dysregulation. Genetic loss of the NF-κB subunit RelB in humans and mice leads to autoimmunity and lethal...
6.
Seitz T, Karabulut A, Suzuki R, Hoffmann A, Heck J, Herres-Pawlis S
Chem Commun (Camb)
. 2025 Feb;
61(18):3684-3687.
PMID: 39918444
We report a novel guanidine quinolinyl entatic state model system with an electron transfer rate on the order of 10 M s and remarkably little internal reorganization. Comparison between this...
7.
Herrmann D, Hodapp P, Starman M, Huang P, Lin C, Le L, et al.
Chem Sci
. 2025 Feb;
16(10):4430-4441.
PMID: 39916882
Analytical data in chemistry and other disciplines is usually generated in different formats and lacks common data and metadata standards that are necessary for a FAIR handling of research data....
8.
Chia J, Singh A, Lin Y, Popko N, Mastro D, Liu Y, et al.
bioRxiv
. 2025 Jan;
PMID: 39868295
Hematopoietic aging is characterized by chronic inflammation associated with myeloid bias, HSC accumulation, and functional HSC impairment. Yet it remains unclear how inflammation promotes these aging phenotypes. NFkappaB both responds...
9.
Lin C, Huang P, Grassle S, Grathwol C, Tremouilhac P, Vanderheiden S, et al.
Sci Data
. 2025 Jan;
12(1):130.
PMID: 39843501
Results of scientific work in chemistry can usually be obtained in the form of materials and data. A big step towards transparency and reproducibility of the scientific work can be...
10.
Singh A, Chia J, Rao D, Hoffmann A
Blood
. 2025 Jan;
PMID: 39791596
Aging and chronic inflammation are associated with overabundant myeloid-primed multipotent progenitors (MPPs) amongst hematopoietic stem and progenitor cells (HSPCs). While HSC differentiation bias has been considered a primary cause of...