Alexander Faussner
Overview
Explore the profile of Alexander Faussner including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
426
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Recent Articles
1.
Doring Y, van der Vorst E, Yan Y, Neideck C, Blanchet X, Jansen Y, et al.
Nat Cardiovasc Res
. 2024 Jul;
3:221-242.
PMID: 39044999
CCL17 is produced by conventional dendritic cells (cDCs), signals through CCR4 on regulatory T cells (Tregs), and drives atherosclerosis by suppressing Treg functions through yet undefined mechanisms. Here we show...
2.
Guillamat-Prats R, Hering D, Derle A, Rami M, Hardtner C, Santovito D, et al.
Nat Cardiovasc Res
. 2022 Dec;
1:1056-1071.
PMID: 36523570
Dissecting the pathways regulating the adaptive immune response in atherosclerosis is of particular therapeutic interest. Here we report that the lipid G-protein coupled receptor GPR55 is highly expressed by splenic...
3.
Faussner A, Deininger M, Weber C, Steffens S
PLoS One
. 2022 Jul;
17(7):e0260173.
PMID: 35802710
For most cell culture experiments, it is indispensable that the cells are firmly anchored to culture plates, withstanding rinsing steps that can create shear forces and tolerating temperature changes without...
4.
Lesage A, Marceau F, Gibson C, Loenders B, Katzer W, Ambrosi H, et al.
Int Immunopharmacol
. 2022 Jan;
105:108523.
PMID: 35086057
PHA-022121 is a novel small molecule bradykinin B receptor antagonist, in clinical development for the treatment and prevention of hereditary angioedema attacks. The present study describes the in vitro pharmacological...
5.
Eckardt V, Miller M, Blanchet X, Duan R, Leberzammer J, Duchene J, et al.
EMBO Rep
. 2020 Feb;
21(4):e47852.
PMID: 32080959
Chemokines and galectins are simultaneously upregulated and mediate leukocyte recruitment during inflammation. Until now, these effector molecules have been considered to function independently. Here, we tested the hypothesis that they...
6.
Guillamat Prats R, Rami M, Ring L, Rinne P, Lauer E, Lenglet S, et al.
Thromb Haemost
. 2019 Jan;
119(2):348-351.
PMID: 30609444
No abstract available.
7.
Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, et al.
Arterioscler Thromb Vasc Biol
. 2018 Mar;
38(5):1007-1019.
PMID: 29567680
Objective: Cardiovascular diseases and depression are the leading causes of disability in Western countries. Clinical data on potential cardiovascular effects of serotonin reuptake inhibitors (SSRIs), the most commonly used antidepressant...
8.
Winkels H, Meiler S, Lievens D, Engel D, Spitz C, Burger C, et al.
Eur Heart J
. 2017 Oct;
38(48):3590-3599.
PMID: 29045618
Aims: The co-stimulatory receptor CD27 modulates responses of T cells, B cells, and NK cells. Various T cell subsets participate in atherogenesis. However, the role of CD27 in atherosclerosis remains...
9.
von Hundelshausen P, Agten S, Eckardt V, Blanchet X, Schmitt M, Ippel H, et al.
Sci Transl Med
. 2017 Apr;
9(384).
PMID: 28381538
Chemokines orchestrate leukocyte trafficking and function in health and disease. Heterophilic interactions between chemokines in a given microenvironment may amplify, inhibit, or modulate their activity; however, a systematic evaluation of...
10.
Winkels H, Meiler S, Smeets E, Lievens D, Engel D, Spitz C, et al.
Thromb Haemost
. 2016 Oct;
117(1):164-175.
PMID: 27786334
The co-stimulatory molecule CD70 is expressed on activated immune cells and is known to modulate responses of T, B, and NK cells via its receptor CD27. Until now, there is...