Alexander Fauland
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Explore the profile of Alexander Fauland including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Safholm J, Abma W, Liu J, Balgoma D, Fauland A, Kolmert J, et al.
Eur J Pharmacol
. 2021 Jun;
907:174282.
PMID: 34175307
The mechanism by which cyclooxygenase (COX) inhibition increases antigen-induced responses in airways remains unknown. Male albino guinea pigs were sensitized to ovalbumin (OVA). Intact rings of the trachea were isolated...
2.
Meuronen T, Lankinen M, Fauland A, Shimizu B, de Mello V, Laaksonen D, et al.
Prostaglandins Leukot Essent Fatty Acids
. 2020 Jun;
159:102143.
PMID: 32512364
n-3 and n-6 polyunsaturated fatty acids (PUFAs) and their lipid mediator metabolites are associated with inflammation. We investigated the effect of dietary intake of plant- and animal-derived n-3 PUFAs and...
3.
Lankinen M, Fauland A, Shimizu B, Agren J, Wheelock C, Laakso M, et al.
Am J Clin Nutr
. 2019 Jan;
109(1):165-175.
PMID: 30624587
Background: The health benefits of substituting dietary polyunsaturated fatty acids (PUFAs) for saturated fatty acids are well known. However, limited information exists on how the response to dietary intake of...
4.
Maric J, Ravindran A, Mazzurana L, Van Acker A, Rao A, Kokkinou E, et al.
J Allergy Clin Immunol
. 2018 Dec;
143(6):2202-2214.e5.
PMID: 30578872
Background: Group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and maintenance of type 2 immune responses. The prostaglandin (PG) D-chemoattractant receptor-homologous molecule expressed on T2...
5.
Kolmert J, Fauland A, Fuchs D, Safholm J, Gomez C, Adner M, et al.
Anal Chem
. 2018 Jul;
90(17):10239-10248.
PMID: 30056696
The clinical importance of prostaglandins and leukotrienes in asthma is well recognized; however, the biochemical role of other lipid mediators (often termed oxylipins) in the regulation of airway tone and...
6.
Kolmert J, Pineiro-Hermida S, Hamberg M, Gregory J, Lopez I, Fauland A, et al.
Prostaglandins Other Lipid Mediat
. 2018 May;
137:20-29.
PMID: 29763661
The profile of activation of lipid mediator (LM) pathways in asthmatic airway inflammation remains unclear. This experimental study quantified metabolite levels of ω3-, ω6- and ω9-derived polyunsaturated fatty acids in...
7.
Hartler J, Triebl A, Ziegl A, Trotzmuller M, Rechberger G, Zeleznik O, et al.
Nat Methods
. 2017 Oct;
14(12):1171-1174.
PMID: 29058722
We achieve automated and reliable annotation of lipid species and their molecular structures in high-throughput data from chromatography-coupled tandem mass spectrometry using decision rule sets embedded in Lipid Data Analyzer...
8.
Bowden J, Heckert A, Ulmer C, Jones C, Koelmel J, Abdullah L, et al.
J Lipid Res
. 2017 Oct;
58(12):2275-2288.
PMID: 28986437
As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950-Metabolites in Frozen...
9.
Lukic A, Larssen P, Fauland A, Samuelsson B, Wheelock C, Gabrielsson S, et al.
FASEB J
. 2017 Jun;
31(10):4370-4381.
PMID: 28637652
M1 and M2 activated macrophages (Mϕs) have different roles in inflammation. Because pathogens may first encounter resting cells, we investigated lipid mediator profiles prior to full activation. Human monocytes were...
10.
Mittal M, Hasan M, Balagunaseelan N, Fauland A, Wheelock C, Radmark O, et al.
Biochim Biophys Acta Gen Subj
. 2017 May;
1861(8):2099-2111.
PMID: 28528958
Background: A 12-lipoxygenase in zebra fish (zf12-LOX) was found to be required for normal embryonic development and LOXs are of great interest for targeted drug designing. In this study, we...