Craig E Wheelock
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Explore the profile of Craig E Wheelock including associated specialties, affiliations and a list of published articles.
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229
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4387
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Recent Articles
1.
Mendez K, Kachroo P, Prince N, Huang M, Cote M, Chu S, et al.
Am J Respir Crit Care Med
. 2025 Feb;
PMID: 39965055
Rationale: Pediatric asthma is heterogeneous, with varied clinical presentations and treatment responses. Metabolomic profiling may uncover shared and unique biological mechanisms across clinical traits that characterize pediatric asthma. Objectives: To...
2.
Sharma R, Mendez K, Begum S, Chu S, Prince N, Hecker J, et al.
EBioMedicine
. 2024 Dec;
112:105534.
PMID: 39740296
Background: There are important inter-relationships between miRNAs and metabolites: alterations in miRNA expression can be induced by various metabolic stimuli, and miRNAs play a regulatory role in numerous cellular processes,...
3.
Revol-Cavalier J, Quaranta A, Newman J, Brash A, Hamberg M, Wheelock C
Chem Rev
. 2024 Dec;
125(1):1-90.
PMID: 39680864
The octadecanoids are a broad class of lipids consisting of the oxygenated products of 18-carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the octadecanoid pathway has...
4.
Dong C, Liu J, Quaranta A, Jing X, Nie M, Wheelock C, et al.
Front Pharmacol
. 2024 Dec;
15:1503648.
PMID: 39650159
Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are important causes of morbidity and mortality in critically ill patients. Gastric contents aspiration is one of the most...
5.
Bohnacker S, Henkel F, Hartung F, Geerlof A, Riemer S, Prodjinotho U, et al.
Sci Immunol
. 2024 Dec;
9(102):eadl1467.
PMID: 39642243
The molecular mechanisms by which worm parasites evade host immunity are incompletely understood. In a mouse model of intestinal helminth infection using (), we show that helminthic glutamate dehydrogenase (heGDH)...
6.
Virkud Y, Styles J, Kelly R, Patil S, Ruiter B, Smith N, et al.
Pediatr Allergy Immunol
. 2024 Nov;
35(11):e14267.
PMID: 39530396
Background: The immunometabolic mechanisms underlying variable responses to oral immunotherapy (OIT) in patients with IgE-mediated food allergy are unknown. Objective: To identify novel pathways associated with tolerance in food allergy,...
7.
Wang G, Hallberg J, Merid S, Kumar A, Klevebro S, Habchi B, et al.
Eur Respir J
. 2024 Oct;
65(1).
PMID: 39467611
Background: Few studies have investigated the influence of body mass index (BMI) trajectories on lung function covering the entire growth period. Methods: We conducted a prospective study using data from...
8.
Smith M, Nie M, Adner M, Safholm J, Wheelock C
Anal Chem
. 2024 Oct;
96(45):17950-17959.
PMID: 39460704
Oxylipins are a class of low-abundance lipids formed via oxygenation of fatty acids. These compounds include potent signaling molecules (e.g., octadecanoids, eicosanoids) that can exert essential functions in the pathophysiology...
9.
Kermani N, Chung K, Macis G, Santini G, Clemeno F, Versi A, et al.
Eur Respir J
. 2024 Oct;
64(5).
PMID: 39401856
Background: Lung quantitative computed tomography (qCT) severe asthma clusters have been reported, but their replication and underlying disease mechanisms are unknown. We identified and replicated qCT clusters of severe asthma...
10.
Torta F, Hoffmann N, Burla B, Alecu I, Arita M, Bamba T, et al.
Nat Commun
. 2024 Oct;
15(1):8562.
PMID: 39362843
In this community effort, we compare measurements between 34 laboratories from 19 countries, utilizing mixtures of labelled authentic synthetic standards, to quantify by mass spectrometry four clinically used ceramide species...