Alexander Buchberger
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Explore the profile of Alexander Buchberger including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1308
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Recent Articles
1.
Kawan M, Korner M, Schlosser A, Buchberger A
Mol Biol Cell
. 2023 Sep;
34(13):ar126.
PMID: 37756124
The endocytic pathway is of central importance for eukaryotic cells, as it enables uptake of extracellular materials, membrane protein quality control and recycling, as well as modulation of receptor signaling....
2.
Korner M, Meyer S, Marincola G, Kern M, Grimm C, Schuelein-Voelk C, et al.
Elife
. 2023 Sep;
12.
PMID: 37713320
The ATPase p97 (also known as VCP, Cdc48) has crucial functions in a variety of important cellular processes such as protein quality control, organellar homeostasis, and DNA damage repair, and...
3.
Schneider C, Erhard F, Binotti B, Buchberger A, Vogel J, Fischer U
Cell Rep
. 2022 Oct;
41(2):111467.
PMID: 36223745
In all domains of life, mechanisms exist that adjust translational capacity to nutrient restriction and other growth constraints. The mammalian target of rapamycin (mTOR) regulates the synthesis of ribosomal proteins...
4.
Tolay N, Buchberger A
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35408984
Eukaryotic cells react to various stress conditions with the rapid formation of membrane-less organelles called stress granules (SGs). SGs form by multivalent interactions between RNAs and RNA-binding proteins and are...
5.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, et al.
Mol Oncol
. 2022 Apr;
16(17):3082-3106.
PMID: 35364627
Oncogenic transformation of lung epithelial cells is a multistep process, frequently starting with the inactivation of tumour suppressors and subsequent development of activating mutations in proto-oncogenes, such as members of...
6.
Buchberger A
Trends Cell Biol
. 2022 Jan;
32(4):278-280.
PMID: 35058103
The protein unfoldase Cdc48/p97 targets a wide variety of cellular substrates, but the molecular basis of substrate turnover remains incompletely understood. Two recent reports, by Ji et al. and van...
7.
Tolay N, Buchberger A
Life Sci Alliance
. 2021 Mar;
4(5).
PMID: 33687997
Stress granules (SGs) are cytoplasmic condensates containing untranslated mRNP complexes. They are induced by various proteotoxic conditions such as heat, oxidative, and osmotic stress. SGs are believed to protect mRNPs...
8.
Turakhiya A, Meyer S, Marincola G, Bohm S, Vanselow J, Schlosser A, et al.
Mol Cell
. 2018 May;
70(5):906-919.e7.
PMID: 29804830
Stress granules (SGs) are cytoplasmic assemblies of mRNPs stalled in translation initiation. They are induced by various stress conditions, including exposure to the environmental toxin and carcinogen arsenic. While perturbed...
9.
Buchberger A, Schindelin H, Hanzelmann P
FEBS Lett
. 2015 Sep;
589(19 Pt A):2578-89.
PMID: 26320413
p97 (also known as Cdc48, Ter94, and VCP) is an essential, abundant and highly conserved ATPase driving the turnover of ubiquitylated proteins in eukaryotes. Even though p97 is involved in...
10.
Buchberger A
Mol Cell
. 2014 Apr;
54(1):3-4.
PMID: 24725593
A novel autophagy pathway eliminates nonnative polytopic membrane proteins from the endoplasmic reticulum that evade degradation by the ubiquitin proteasome system.