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Alexander Bick

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Articles 27
Citations 871
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Recent Articles
11.
Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat M, Kentistou K, et al.
medRxiv . 2023 Feb; PMID: 36778285
Mosaic loss of the X chromosome (mLOX) is the most commonly occurring clonal somatic alteration detected in the leukocytes of women, yet little is known about its genetic determinants or...
12.
Bick A, Blandin A
Rev Econ Dyn . 2022 Nov; 49:58-76. PMID: 36415762
Economists have recently begun using independent online surveys to collect national labor market data. Questions remain over the quality of such data. This paper provides an approach to address these...
13.
Lamberg M, Rossman A, Bennett A, Painter S, Goodman R, MacLeod J, et al.
Curr Atheroscler Rep . 2022 Apr; 24(6):443-456. PMID: 35441347
Purpose Of Review: Cardiovascular disease (CVD) and cancer are the first and second most common causes of death within the USA. It is well established that a diagnosis of cancer...
14.
Dou H, Kotini A, Liu W, Fidler T, Endo-Umeda K, Sun X, et al.
Circulation . 2021 Nov; 144(24):1940-1954. PMID: 34846914
Background: LNK/SH2B3 inhibits Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling by hematopoietic cytokine receptors. Genome-wide association studies have shown association of a common single nucleotide polymorphism in (R262W,...
15.
Kim P, Niroula A, Shkolnik V, McConkey M, Lin A, Slabicki M, et al.
J Exp Med . 2021 Oct; 218(12). PMID: 34698806
Osteoporosis is caused by an imbalance of osteoclasts and osteoblasts, occurring in close proximity to hematopoietic cells in the bone marrow. Recurrent somatic mutations that lead to an expanded population...
16.
Verma A, Tsao N, Thomann L, Ho Y, Iyengar S, Luoh S, et al.
medRxiv . 2021 Oct; PMID: 34642702
The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of...
17.
Marnell C, Bick A, Natarajan P
J Mol Cell Cardiol . 2021 Jul; 161:98-105. PMID: 34298011
Clonal hematopoiesis of indeterminate potential (CHIP) is the presence of a clonally expanded hematopoietic stem cell caused by a leukemogenic mutation in individuals without evidence of hematologic malignancy, dysplasia, or...
18.
Bhattacharya R, Zekavat S, Uddin M, Pirruccello J, Niroula A, Gibson C, et al.
JAMA Cardiol . 2021 Jun; 6(9):1069-1077. PMID: 34106216
Importance: Clonal hematopoiesis of indeterminate potential (CHIP), the expansion of somatic leukemogenic variations in hematopoietic stem cells, has been associated with atherosclerotic cardiovascular disease. Because the inherited risk of developing...
19.
Emdin C, Haas M, Khera A, Aragam K, Chaffin M, Klarin D, et al.
PLoS Genet . 2021 Apr; 17(4):e1009503. PMID: 33822779
[This corrects the article DOI: 10.1371/journal.pgen.1008629.].
20.
Natarajan P, Zekavat S, Lin S, Bick A, Liu A, Paruchuri K, et al.
Res Sq . 2020 Nov; PMID: 33236004
Age is the dominant risk factor for infectious diseases, but the mechanisms linking the two are incompletely understood1,2. Age-related mosaic chromosomal alterations (mCAs) detected from blood-derived DNA genotyping, are structural...