Alexander Bick
Overview
Explore the profile of Alexander Bick including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
871
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Recent Articles
1.
Zorc R, Redmond C, Sylvester M, Maclean M, Yamamoto de Almeida L, Quinn K, et al.
Ann Rheum Dis
. 2025 Feb;
PMID: 40000263
Objectives: The study objective was to determine if a common single nucleotide polymorphism in the interleukin 6 (IL-6) receptor (rs2228145, p.Asp358Ala) predicted treatment response to tocilizumab in giant cell arteritis...
2.
Stubbs D, Hooker G, Li Y, Richter L, Bick A
Genet Med Open
. 2024 Dec;
1(1):100822.
PMID: 39669253
Purpose: As polygenic risk scores (PRSs) enter clinical practice, health care providers' and the publics' comprehension of PRS results are of great importance; yet, they are poorly understood. We present...
3.
Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat S, Kentistou K, et al.
Nature
. 2024 Dec;
636(8043):E7.
PMID: 39627447
No abstract available.
4.
Weinstock J, Chaudhry S, Ioannou M, Viskadourou M, Reventun P, Jakubek Y, et al.
medRxiv
. 2024 Sep;
PMID: 39228737
Clonal hematopoiesis (CH) is defined by the expansion of a lineage of genetically identical cells in blood. Genetic lesions that confer a fitness advantage, such as point mutations or mosaic...
5.
Levy D, Kirmani S, Huan T, Van Amburg J, Joehanes R, Uddin M, et al.
Res Sq
. 2024 Jul;
PMID: 39070619
With age, hematopoietic stem cells can acquire somatic mutations in leukemogenic genes that confer a proliferative advantage in a phenomenon termed "clonal hematopoiesis of indeterminate potential" (CHIP). How these mutations...
6.
Desai P, Zhou Y, Grenet J, Handelman S, Crispino C, Tarbay L, et al.
Cancer
. 2024 Jul;
130(22):3879-3887.
PMID: 39012906
Background: Understanding the impact of clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) on solid tumor risk and mortality can shed light on novel cancer pathways. Methods:...
7.
Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat S, Kentistou K, et al.
Nature
. 2024 Jun;
631(8019):134-141.
PMID: 38867047
Mosaic loss of the X chromosome (mLOX) is the most common clonal somatic alteration in leukocytes of female individuals, but little is known about its genetic determinants or phenotypic consequences....
8.
Mack T, Vlasschaert C, von Beck K, Silver A, Heimlich J, Poisner H, et al.
medRxiv
. 2023 Nov;
PMID: 37986782
Clonal hematopoiesis of indeterminate potential (CHIP) is a common age-related phenomenon that occurs when hematopoietic stem cells acquire mutations in a select set of genes commonly mutated in myeloid neoplasia...
9.
Robinson-Cohen C, Triozzi J, Rowan B, He J, Chen H, Zheng N, et al.
J Am Soc Nephrol
. 2023 Jun;
34(9):1547-1559.
PMID: 37261792
Significance Statement: Rapid progression of CKD is associated with poor clinical outcomes. Most previous studies looking for genetic factors associated with low eGFR have used cross-sectional data. The authors conducted...
10.
Wheless L, Pike M, Chen H, Yu Z, Tao R, Bick A, et al.
Kidney360
. 2023 Feb;
4(2):241-244.
PMID: 36821615
No abstract available.