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Alexander A Green

Explore the profile of Alexander A Green including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 1981
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Recent Articles
1.
Zhou Y, Sheng P, Li J, Li Y, Xie M, Green A
Nat Commun . 2024 Aug; 15(1):6855. PMID: 39127751
RNA interference (RNAi) is a powerful tool for sequence-specific gene knockdown in therapeutic and research applications. However, spatiotemporal control of RNAi is required to decrease nonspecific targeting, potential toxicity, and...
2.
Yan Z, Eshed A, Tang A, Arevalos N, Ticktin Z, Chaudhary S, et al.
Chem . 2024 Jul; 10(7):2220-2244. PMID: 39036067
Rapid, simple, and low-cost diagnostic technologies are crucial tools for combatting infectious disease. We describe a class of aptamer-based RNA switches or aptaswitches that recognize target nucleic acid molecules and...
3.
Riley A, Robson J, Green A
bioRxiv . 2023 Jul; PMID: 37503279
RNA is a remarkably versatile molecule that has been engineered for applications in therapeutics, diagnostics, and information-processing systems. However, the complex relationship between the sequence and structural properties of an...
4.
Yan Z, Tang A, Eshed A, Ticktin Z, Chaudhary S, Ma D, et al.
medRxiv . 2023 Jun; PMID: 37333364
Rapid, simple, and low-cost diagnostic technologies are crucial tools for combatting infectious disease. Here, we describe a class of aptamer-based RNA switches called aptaswitches that recognize specific target nucleic acid...
5.
Wu K, Green A
Nat Biomed Eng . 2022 Aug; 6(8):928-929. PMID: 35986183
No abstract available.
6.
Jaenes K, da Silva S, Vigar J, Wu K, Norouzi M, Bayat P, et al.
J Vis Exp . 2022 Jul; (184). PMID: 35781278
Access to low-burden molecular diagnostics that can be deployed into the community for testing is increasingly important and has meaningful wider implications for the well-being of societies and economic stability....
7.
Robson J, Green A
Proc Natl Acad Sci U S A . 2022 Jun; 119(25):e2205897119. PMID: 35687665
No abstract available.
8.
McCutcheon G, Chaudhary S, Hong S, Park D, Kim J, Green A
Methods Mol Biol . 2022 Jun; 2518:65-86. PMID: 35666439
The ability to control cell function is a critical goal for synthetic biology and motivates the development of ever-improving methods for precise regulation of gene expression. RNA-based systems represent powerful...
9.
Hong S, Park D, Chaudhary S, McCutcheon G, Green A, Kim J
Methods Mol Biol . 2022 Jun; 2518:49-64. PMID: 35666438
The toehold switch is an RNA-based riboregulator that activates translation in response to a cognate trigger RNA and provides high ON/OFF ratios, excellent orthogonality, and logic capabilities. Riboregulators that provide...
10.
Wu K, Yan Z, Green A
Methods Mol Biol . 2022 Jun; 2518:33-47. PMID: 35666437
Translation activators are an important class of riboregulators that respond to nucleic acid signals by activating gene expression. Toehold switches and single-nucleotide-specific programmable riboregulators (SNIPRs) are two types of translation...