Alex Warwick Vesztrocy
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Explore the profile of Alex Warwick Vesztrocy including associated specialties, affiliations and a list of published articles.
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14
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Recent Articles
1.
Majidian S, Nevers Y, Yazdizadeh Kharrazi A, Warwick Vesztrocy A, Pascarelli S, Moi D, et al.
Nat Methods
. 2025 Jan;
22(2):269-272.
PMID: 39753922
The surge in genome data, with ongoing efforts aiming to sequence 1.5 M eukaryotes in a decade, could revolutionize genomics, revealing the origins, evolution and genetic innovations of biological processes....
2.
Nevers Y, Warwick Vesztrocy A, Rossier V, Train C, Altenhoff A, Dessimoz C, et al.
Nat Biotechnol
. 2024 Feb;
43(1):124-133.
PMID: 38383603
In the era of biodiversity genomics, it is crucial to ensure that annotations of protein-coding gene repertoires are accurate. State-of-the-art tools to assess genome annotations measure the completeness of a...
3.
Altenhoff A, Warwick Vesztrocy A, Bernard C, Train C, Nicheperovich A, Prieto Banos S, et al.
Nucleic Acids Res
. 2023 Nov;
52(D1):D513-D521.
PMID: 37962356
In this update paper, we present the latest developments in the OMA browser knowledgebase, which aims to provide high-quality orthology inferences and facilitate the study of gene families, genomes and...
4.
Rossier V, Warwick Vesztrocy A, Robinson-Rechavi M, Dessimoz C
Bioinformatics
. 2021 Mar;
37(18):2866-2873.
PMID: 33787851
Motivation: Assigning new sequences to known protein families and subfamilies is a prerequisite for many functional, comparative and evolutionary genomics analyses. Such assignment is commonly achieved by looking for the...
5.
Altenhoff A, Train C, Gilbert K, Mediratta I, Mendes de Farias T, Moi D, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D373-D379.
PMID: 33174605
OMA is an established resource to elucidate evolutionary relationships among genes from currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise orthologs, functional annotations, local and...
6.
Warwick Vesztrocy A, Dessimoz C
Bioinformatics
. 2020 Jul;
36(Suppl_1):i210-i218.
PMID: 32657372
Motivation: With the ever-increasing number and diversity of sequenced species, the challenge to characterize genes with functional information is even more important. In most species, this characterization almost entirely relies...
7.
Ducrest A, Neuenschwander S, Schmid-Siegert E, Pagni M, Train C, Dylus D, et al.
Ecol Evol
. 2020 Mar;
10(5):2284-2298.
PMID: 32184981
New genomic tools open doors to study ecology, evolution, and population genomics of wild animals. For the Barn owl species complex, a cosmopolitan nocturnal raptor, a very fragmented draft genome...
8.
Zhou N, Jiang Y, Bergquist T, Lee A, Kacsoh B, Crocker A, et al.
Genome Biol
. 2019 Nov;
20(1):244.
PMID: 31744546
Background: The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function. Results: Here, we report on the...
9.
Altenhoff A, Levy J, Zarowiecki M, Tomiczek B, Warwick Vesztrocy A, Dalquen D, et al.
Genome Res
. 2019 Jun;
29(7):1152-1163.
PMID: 31235654
Genomes and transcriptomes are now typically sequenced by individual laboratories but analyzing them often remains challenging. One essential step in many analyses lies in identifying orthologs-corresponding genes across multiple species-but...
10.
Kaleb K, Warwick Vesztrocy A, Altenhoff A, Dessimoz C
F1000Res
. 2019 Apr;
8:42.
PMID: 31001419
The Orthologous Matrix (OMA) is a well-established resource to identify orthologs among many genomes. Here, we present two recent additions to its programmatic interface, namely a REST API, and user-friendly...