Alex T Adai
Overview
Explore the profile of Alex T Adai including associated specialties, affiliations and a list of published articles.
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13
Citations
1101
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0
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Recent Articles
1.
Choudhary A, Mambo E, Sanford T, Boedigheimer M, Twomey B, Califano J, et al.
BMC Med Genomics
. 2014 Nov;
7:62.
PMID: 25395014
Background: Improvements in both performance and cost for next-generation sequencing (NGS) have spurred its rapid adoption for clinical applications. We designed and optimized a pan-cancer target-enrichment panel for 51 well-established...
2.
A microRNA-based test improves endoscopic ultrasound-guided cytologic diagnosis of pancreatic cancer
Brand R, Adai A, Centeno B, Lee L, Rateb G, Vignesh S, et al.
Clin Gastroenterol Hepatol
. 2014 Mar;
12(10):1717-23.
PMID: 24662333
Background & Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in combination with cytopathology is the optimal method for diagnosis and staging of pancreatic ductal adenocarcinoma (PDAC) and other pancreatic lesions. Its...
3.
Hadd A, Houghton J, Choudhary A, Sah S, Chen L, Marko A, et al.
J Mol Diagn
. 2013 Jan;
15(2):234-47.
PMID: 23321017
Implementation of highly sophisticated technologies, such as next-generation sequencing (NGS), into routine clinical practice requires compatibility with common tumor biopsy types, such as formalin-fixed, paraffin-embedded (FFPE) and fine-needle aspiration specimens,...
4.
Matthaei H, Wylie D, Lloyd M, Dal Molin M, Kemppainen J, Mayo S, et al.
Clin Cancer Res
. 2012 Jun;
18(17):4713-24.
PMID: 22723372
Purpose: The diagnosis of pancreatic cystic lesions has increased dramatically. Most are benign, whereas some, such as intraductal papillary mucinous neoplasms (IPMN), represent precursors of pancreatic adenocarcinoma. Therapeutic stratification of...
5.
Wylie D, Shelton J, Choudhary A, Adai A
BMC Res Notes
. 2011 Dec;
4:555.
PMID: 22188771
Background: Normalization is critical for accurate gene expression analysis. A significant challenge in the quantitation of gene expression from biofluids samples is the inability to quantify RNA concentration prior to...
6.
Munding J, Adai A, Maghnouj A, Urbanik A, Zollner H, Liffers S, et al.
Int J Cancer
. 2011 Sep;
131(2):E86-95.
PMID: 21953293
Pancreatic ductal adenocarcinoma (PDAC) is known for its poor prognosis resulting from being diagnosed at an advanced stage. Accurate early diagnosis and new therapeutic modalities are therefore urgently needed. MicroRNAs...
7.
Stinson S, Lackner M, Adai A, Yu N, Kim H, OBrien C, et al.
Sci Signal
. 2011 Aug;
4(186):pt5.
PMID: 21868360
Compared with the luminal subtype, the basal-like subtype of breast cancer has an aggressive clinical behavior, but the reasons for this difference between the two subtypes are poorly understood. We...
8.
Stinson S, Lackner M, Adai A, Yu N, Kim H, OBrien C, et al.
Sci Signal
. 2011 Jun;
4(177):ra41.
PMID: 21673316
The basal-like subtype of breast cancer has an aggressive clinical behavior compared to that of the luminal subtype. We identified the microRNAs (miRNAs) miR-221 and miR-222 (miR-221/222) as basal-like subtype-specific...
9.
Szafranska-Schwarzbach A, Adai A, Lee L, Conwell D, Andruss B
Expert Rev Mol Diagn
. 2011 Apr;
11(3):249-57.
PMID: 21463235
Diagnosis of pancreatic cancer remains a clinical challenge. Both chronic pancreatitis and pancreatic cancer may present with similar symptoms and similar imaging features, often leading to incorrect interpretation. Thus, the...
10.
Johnson C, Bowman L, Adai A, Vance V, Sundaresan V
Nucleic Acids Res
. 2006 Dec;
35(Database issue):D829-33.
PMID: 17169981
Plant small RNAs (smRNAs), which include microRNAs (miRNAs), short interfering RNAs (siRNAs) and trans-acting siRNAs (ta-siRNAs), are emerging as significant components of epigenetic processes and of gene networks involved in...