Alex M Mooney
Overview
Explore the profile of Alex M Mooney including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
207
Followers
0
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Recent Articles
1.
North J, Simon M, Ferdinand M, Shoffner M, Picking J, Howard C, et al.
Nucleic Acids Res
. 2014 Feb;
42(8):4922-33.
PMID: 24561803
Nucleosomes contain ∼146 bp of DNA wrapped around a histone protein octamer that controls DNA accessibility to transcription and repair complexes. Posttranslational modification (PTM) of histone proteins regulates nucleosome function....
2.
Sen P, Vivas P, Dechassa M, Mooney A, Poirier M, Bartholomew B
Mol Cell Biol
. 2012 Nov;
33(2):360-70.
PMID: 23149935
The SWI/SNF chromatin remodeling complex changes the positions where nucleosomes are bound to DNA, exchanges out histone dimers, and disassembles nucleosomes. All of these activities depend on ATP hydrolysis by...
3.
North J, Shimko J, Javaid S, Mooney A, Shoffner M, Rose S, et al.
Nucleic Acids Res
. 2012 Sep;
40(20):10215-27.
PMID: 22965129
Eukaryotic genomes are repetitively wrapped into nucleosomes that then regulate access of transcription and DNA repair complexes to DNA. The mechanisms that regulate extrinsic protein interactions within nucleosomes are unresolved....
4.
Manohar M, Mooney A, North J, Nakkula R, Picking J, Edon A, et al.
J Biol Chem
. 2009 Jun;
284(35):23312-21.
PMID: 19520870
Histone post-translational modifications are essential for regulating and facilitating biological processes such as RNA transcription and DNA repair. Fifteen modifications are located in the DNA-histone dyad interface and include the...