Alex Hatzimanolis
Overview
Explore the profile of Alex Hatzimanolis including associated specialties, affiliations and a list of published articles.
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29
Citations
1195
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Recent Articles
1.
Sampatakakis S, Mourtzi N, Hatzimanolis A, Koutsis G, Charisis S, Gkelmpesi I, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940679
In the present study, we investigated the association of genetic predisposition with specific dimensions of dementia pathophysiology for global and domain-specific cognitive decline in older adults. The sample was drawn...
2.
Liampas I, Siokas V, Mourtzi N, Charisis S, Sampatakakis S, Foukarakis I, et al.
Geriatrics (Basel)
. 2025 Jan;
10(1.
PMID: 39846584
Background: There is a paucity of evidence on the association between genetic propensity for hippocampal atrophy with cognitive outcomes. Therefore, we examined the relationship of the polygenic risk score for...
3.
Hatzimanolis A, Foteli S, Xenaki L, Selakovic M, Dimitrakopoulos S, Vlachos I, et al.
Schizophrenia (Heidelb)
. 2024 Jul;
10(1):61.
PMID: 38987245
The tryptophan-metabolizing kynurenine pathway (KP) can be activated by enhanced inflammatory responses and has been implicated in the pathophysiology of schizophrenia. However, there is little evidence for KP dysregulation in...
4.
Sampatakakis S, Mourtzi N, Charisis S, Kalligerou F, Mamalaki E, Ntanasi E, et al.
Biomedicines
. 2024 May;
12(5).
PMID: 38791015
The possible relationship between Subjective Cognitive Decline (SCD) and dementia needs further investigation. In the present study, we explored the association between specific biomarkers of Alzheimer's Disease (AD), amyloid-beta 42...
5.
Sampatakakis S, Mourtzi N, Charisis S, Mamalaki E, Ntanasi E, Hatzimanolis A, et al.
Clin Neuropsychol
. 2024 May;
39(1):83-99.
PMID: 38741352
Our study aimed to explore whether physical condition might affect the association between genetic predisposition for Alzheimer's Disease (AD) and AD incidence. The sample of participants consisted of 561 community-dwelling...
6.
Hatzimanolis A, Tosato S, Ruggeri M, Cristofalo D, Mantonakis L, Xenaki L, et al.
Transl Psychiatry
. 2024 Jan;
14(1):36.
PMID: 38238289
Insufficiency of vitamin D levels often occur in individuals with schizophrenia and first-episode psychosis (FEP). However, it is unknown whether this represents a biological predisposition, or it is essentially driven...
7.
Legaki E, Tsaklakidou D, Hatzimanolis A, Segredou E, Petalotis M, Moularogiorgou G, et al.
In Vivo
. 2022 Sep;
36(5):2092-2104.
PMID: 36099111
Background/aim: Alcohol use disorder (AUD) is a chronic, multifactorial psychiatric condition with an enormous impact on public health and social cost. Genetic studies suggest a heritability, and genome-wide association studies...
8.
Liampas I, Hatzimanolis A, Siokas V, Yannakoulia M, Kosmidis M, Sakka P, et al.
J Alzheimers Dis
. 2022 Aug;
89(2):709-719.
PMID: 35912747
Background: It is unclear whether the main antihypertensive medication classes (diuretics, calcium channel blockers, beta-blockers, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers (ARBs)) are associated with different risks of...
9.
Hatzimanolis A, Foteli S, Stefanatou P, Ntigrintaki A, Ralli I, Kollias K, et al.
Eur Arch Psychiatry Clin Neurosci
. 2022 May;
272(7):1219-1228.
PMID: 35532796
Up-regulation of the complement component 4A (C4A) in the brain has been associated with excessive synaptic pruning and increased schizophrenia (SZ) susceptibility. Over-expression of C4A has been observed in SZ...
10.
Tsapanou A, Mourtzi N, Charisis S, Hatzimanolis A, Ntanasi E, Kosmidis M, et al.
Genes (Basel)
. 2022 Jan;
13(1).
PMID: 35052403
Sleep problems have been associated with cognition, both cross-sectionally and longitudinally. Specific genes have been also associated with both sleep regulation and cognition. In a large group of older non-demented...