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Todd Lencz

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Articles 187
Citations 9416
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Recent Articles
1.
Bhattacharyya U, John J, Lam M, Fisher J, Sun B, Baird D, et al.
JAMA Psychiatry . 2025 Mar; PMID: 40072421
Importance: Peripheral (blood-based) biomarkers for psychiatric illness could benefit diagnosis and treatment, but research to date has typically been low throughput, and traditional case-control studies are subject to potential confounds...
2.
Velioglu H, Moehringer J, Lencz T, Gallego J, Cholewa J, Kats Y, et al.
Schizophr Bull . 2025 Mar; PMID: 40063595
Background: The cerebellum has traditionally been associated with motor functions, but recent evidence highlights its critical role in cognitive and emotional regulation, contributing to the neuropathology of schizophrenia. Our previous...
3.
Bhattacharyya U, John J, Lencz T, Lam M
Biol Psychiatry . 2025 Feb; PMID: 39993652
Background: Given the increasingly large number of loci discovered by psychiatric GWAS, specification of the key biological pathways underlying these loci has become a priority for the field. We have...
4.
Gallego J, Palade J, Alsop E, Hutchins E, Hsieh M, Logerman A, et al.
medRxiv . 2025 Feb; PMID: 39974022
Biomarkers that are clinically useful for the diagnosis and treatment of schizophrenia are lacking. Biomarkers are critical tools that reduce the incidence of misdiagnosis, identify subgroups of patients, assist in...
5.
Hatoum A, Davis C, Kember R, Johnstone M, Oslin D, Zinkstok J, et al.
Lancet Psychiatry . 2024 Oct; 12(2):94-95. PMID: 39413801
No abstract available.
6.
Franklin C, Achtyes E, Altinay M, Bailey K, Bhati M, Carr B, et al.
Mol Psychiatry . 2024 Oct; 30(3):1117-1126. PMID: 39406997
Genome-wide association studies (GWASs) of major depressive disorder (MDD) have recently achieved extremely large sample sizes and yielded substantial numbers of genome-wide significant loci. Because of the approach to ascertainment...
7.
Finnerty M, Khan A, You K, Wang R, Gu G, Layman D, et al.
Schizophrenia (Heidelb) . 2024 Aug; 10(1):68. PMID: 39174558
Given the chronic nature of schizophrenia, it is important to examine age-specific prevalence and incidence to understand the scope of the burden of schizophrenia across the lifespan. Estimates of lifetime...
8.
Capalbo A, de Wert G, Mertes H, Klausner L, Coonen E, Spinella F, et al.
Hum Reprod Update . 2024 May; 30(5):529-557. PMID: 38805697
Background: The genetic composition of embryos generated by in vitro fertilization (IVF) can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited to detecting single-gene, high-risk pathogenic...
9.
Furrer R, Barlevy D, Pereira S, Carmi S, Lencz T, Lazaro-Munoz G
JAMA Netw Open . 2024 May; 7(5):e2410832. PMID: 38743425
Importance: Polygenic embryo screening (PES) is a novel technology that estimates the likelihood of developing future conditions (eg, diabetes or depression) and traits (eg, height or cognitive ability) in human...
10.
Bhattacharyya U, John J, Lencz T, Lam M
medRxiv . 2024 May; PMID: 38699340
Given the increasingly large number of loci discovered by psychiatric GWAS, specification of the key biological pathways underlying these loci has become a priority for the field. We have previously...