Alessio Cantore
Overview
Explore the profile of Alessio Cantore including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1277
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Recent Articles
1.
Simoni C, Nozi J, Starinieri F, La Bella T, Manta E, Negri C, et al.
Nat Commun
. 2025 Mar;
16(1):2119.
PMID: 40064848
Liver fibrosis occurs in several genetic and acquired disease conditions, leading to alterations of the tissue and metabolism, which may adversely affect viral vector-mediated gene therapy. Here, we assessed the...
2.
Milani M, Starinieri F, Fabiano A, Beretta S, Plati T, Canepari C, et al.
Cell Rep
. 2025 Feb;
44(3):115341.
PMID: 39998949
Liver regeneration is supported by hepatocytes and, in certain conditions, biliary epithelial cells (BECs). BECs are facultative liver stem cells that form organoids in culture and engraft in damaged livers....
3.
Cattaneo S, Bettegazzi B, Crippa L, Asth L, Regoni M, Soukupova M, et al.
EMBO Rep
. 2024 Sep;
25(10):4387-4409.
PMID: 39251828
Gene therapy is emerging as an alternative option for individuals with drug-resistant focal epilepsy. Here, we explore the potential of a novel gene therapy based on Neuropeptide Y (NPY), a...
4.
Simoni C, Barbon E, Muro A, Cantore A
Front Genome Ed
. 2024 Sep;
6:1458037.
PMID: 39246827
The liver is an essential organ of the body that performs several vital functions, including the metabolism of biomolecules, foreign substances, and toxins, and the production of plasma proteins, such...
5.
Canepari C, Cantore A
Front Mol Med
. 2024 Aug;
3:1140997.
PMID: 39086674
Familial hypercholesterolemia (FH) is an autosomal dominant inherited disease characterized by high circulating low-density lipoprotein (LDL) cholesterol. High circulating LDL cholesterol in FH is due to dysfunctional LDL receptors, and...
6.
Milani M, Canepari C, Assanelli S, Merlin S, Borroni E, Starinieri F, et al.
EMBO Mol Med
. 2024 Apr;
16(6):1427-1450.
PMID: 38684862
Lentiviral vectors (LV) are efficient vehicles for in vivo gene delivery to the liver. LV integration into the chromatin of target cells ensures their transmission upon proliferation, thus allowing potentially...
7.
Annoni A, Cantore A
Mol Ther Nucleic Acids
. 2024 Feb;
35(1):102144.
PMID: 38384446
No abstract available.
8.
Ho N, Agarwal S, Milani M, Cantore A, Buchholz C, Thalheimer F
Mol Ther Methods Clin Dev
. 2022 Jul;
26:144-156.
PMID: 35795778
Pre-clinical humanized mouse models are a powerful tool to evaluate immunotherapies. NSG-SGM3 mice reconstituted with human stem cells (huSGM3) develop pronounced human myeloid cells due to transgenic expression of stem...
9.
Milani M, Canepari C, Liu T, Biffi M, Russo F, Plati T, et al.
Nat Commun
. 2022 May;
13(1):2454.
PMID: 35508619
Liver gene therapy with adeno-associated viral (AAV) vectors delivering clotting factor transgenes into hepatocytes has shown multiyear therapeutic benefit in adults with hemophilia. However, the mostly episomal nature of AAV...
10.
Cantore A, Fraldi A, Meneghini V, Gritti A
Front Med (Lausanne)
. 2022 Feb;
8:774618.
PMID: 35118085
genetic engineering has recently shown remarkable potential as a novel effective treatment for an ever-growing number of diseases, as also witnessed by the recent marketing authorization of several gene therapy...