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Alessandro Rimessi

Explore the profile of Alessandro Rimessi including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 4134
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Recent Articles
1.
Jakubek P, Pakula B, Rossmeisl M, Pinton P, Rimessi A, Wieckowski M
Intern Emerg Med . 2024 Nov; 20(1):333. PMID: 39589635
No abstract available.
2.
Jakubek P, Pakula B, Rossmeisl M, Pinton P, Rimessi A, Wieckowski M
Intern Emerg Med . 2024 Jul; 19(5):1473-1491. PMID: 38971910
Autophagy is an evolutionarily conserved process that plays a pivotal role in the maintenance of cellular homeostasis and its impairment has been implicated in the pathogenesis of various metabolic diseases...
3.
Palumbo L, Carinci M, Guarino A, Asth L, Zucchini S, Missiroli S, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893198
Neuroinflammation represents a dynamic process of defense and protection against the harmful action of infectious agents or other detrimental stimuli in the central nervous system (CNS). However, the uncontrolled regulation...
4.
Pellielo G, Agyapong E, Pinton P, Rimessi A
Int Rev Cell Mol Biol . 2023 Jun; 377:19-43. PMID: 37268349
Cystic fibrosis (CF) is a genetic disease characterized by mutations of cystic fibrosis transmembrane conductance regulator (CFTR) gene, which lead to a dysfunctional chloride and bicarbonate channel. Abnormal mucus viscosity,...
5.
Di Mambro T, Pellielo G, Agyapong E, Carinci M, Chianese D, Giorgi C, et al.
Int J Mol Sci . 2023 May; 24(9). PMID: 37175888
Mitochondria are organelles present in almost all eukaryotic cells, where they represent the main site of energy production. Mitochondria are involved in several important cell processes, such as calcium homeostasis,...
6.
Bezzerri V, Gentili V, Api M, Finotti A, Papi C, Tamanini A, et al.
Nat Commun . 2023 Jan; 14(1):132. PMID: 36627352
As an inherited disorder characterized by severe pulmonary disease, cystic fibrosis could be considered a comorbidity for coronavirus disease 2019. Instead, current clinical evidence seems to be heading in the...
7.
Costantino L, Ferrari S, Santucci M, Salo-Ahen O, Carosati E, Franchini S, et al.
Elife . 2022 Dec; 11. PMID: 36475542
Drugs that target human thymidylate synthase (hTS), a dimeric enzyme, are widely used in anticancer therapy. However, treatment with classical substrate-site-directed TS inhibitors induces over-expression of this protein and development...
8.
Carinci M, Palumbo L, Pellielo G, Agyapong E, Morciano G, Patergnani S, et al.
Biomedicines . 2022 Aug; 10(8). PMID: 36009490
Autophagy is a highly conserved dynamic process by which cells deliver their contents to lysosomes for degradation, thus ensuring cell homeostasis. In response to environmental stress, the induction of autophagy...
9.
Vitto V, Bianchin S, Zolondick A, Pellielo G, Rimessi A, Chianese D, et al.
Biomedicines . 2022 Jul; 10(7). PMID: 35884904
Autophagy is an evolutionarily conserved and tightly regulated process that plays an important role in maintaining cellular homeostasis. It involves regulation of various genes that function to degrade unnecessary or...
10.
Patergnani S, Morciano G, Carinci M, Leo S, Pinton P, Rimessi A
Neural Regen Res . 2022 Jun; 17(12):2563-2575. PMID: 35662183
Neuronal disorders are associated with a profound loss of mitochondrial functions caused by various stress conditions, such as oxidative and metabolic stress, protein folding or import defects, and mitochondrial DNA...