Alessandro Paoli
Overview
Explore the profile of Alessandro Paoli including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
186
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0
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Recent Articles
1.
Zicari S, Merlino G, Paoli A, Fiascarelli A, Tunici P, Bisignano D, et al.
J Cell Mol Med
. 2024 Dec;
28(23):e70235.
PMID: 39653657
MEN1703 is a first-in-class, oral, Type I dual PIM/FMS-like tyrosine kinase 3 inhibitor (FLT3i) investigated in a Phase I/II DIAMOND-01 trial in patients with acute myeloid leukaemia (AML). Gilteritinib is...
2.
Tosi G, Paoli A, Zuccolotto G, Turco E, Simonato M, Tosoni D, et al.
Nat Commun
. 2024 Sep;
15(1):8214.
PMID: 39294175
CoQ (Coenzyme Q) is an essential fat-soluble metabolite that plays a key role in cellular metabolism. A less-known function of CoQ is whether it may act as a plasma membrane-stabilizing...
3.
Bardia A, Cortes J, Bidard F, Neven P, Garcia-Saenz J, Aftimos P, et al.
Clin Cancer Res
. 2024 Aug;
30(19):4299-4309.
PMID: 39087959
Purpose: Elacestrant significantly prolonged progression-free survival (PFS) with manageable safety versus standard-of-care (SOC) endocrine therapy (ET) in patients with estrogen receptor-positive (ER+), HER2- metastatic breast cancer and tumors harboring estrogen...
4.
Angelo L, Di Stefano P, Guardiani E, Neri P, Paoli A, Razionale A
Sensors (Basel)
. 2023 Sep;
23(18).
PMID: 37765897
Digital representations of anatomical parts are crucial for various biomedical applications. This paper presents an automatic alignment procedure for creating accurate 3D models of upper limb anatomy using a low-cost...
5.
Augimeri G, Gonzalez M, Paoli A, Eido A, Choi Y, Burman B, et al.
JCI Insight
. 2023 Aug;
8(18).
PMID: 37607007
Patients with triple-negative breast cancer remain at risk for metastatic disease despite treatment. The acquisition of chemoresistance is a major cause of tumor relapse and death, but the mechanisms are...
6.
Naimo G, Forestiero M, Paoli A, Malivindi R, Gelsomino L, Gyorffy B, et al.
Int J Cancer
. 2023 Jun;
153(6):1257-1272.
PMID: 37323038
Adiponectin is the major adipocytes-secreted protein involved in obesity-related breast cancer growth and progression. We proved that adiponectin promotes proliferation in ERα-positive breast cancer cells, through ERα transactivation and the...
7.
Naimo G, Paoli A, Giordano F, Forestiero M, Panno M, Ando S, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37240258
Obesity has a noteworthy role in breast tumor initiation and progression. Among the mechanisms proposed, the most validated is the development of chronic low-grade inflammation, supported by immune cell infiltration...
8.
Fiascarelli A, Merlino G, Capano S, Talucci S, Bisignano D, Bressan A, et al.
Breast Cancer Res Treat
. 2023 Mar;
199(1):13-23.
PMID: 36913051
Purpose: Dysregulation of the PI3K pathway is one of the most common events in breast cancer. Here we investigate the activity of the PI3K inhibitor MEN1611 at both molecular and...
9.
Giordano F, Paoli A, Forastiero M, Marsico S, De Amicis F, Marrelli M, et al.
J Transl Med
. 2023 Mar;
21(1):165.
PMID: 36864445
Background: Breast cancer is the second leading cause of death among women after lung cancer. Despite the improvement in prevention and in therapy, breast cancer still remains a threat, both...
10.
Jo J, Folz J, Gonzalez M, Paoli A, Eido A, Salfi E, et al.
ACS Nano
. 2023 Feb;
17(5):4396-4403.
PMID: 36847392
We hereby apply the approach of photoacoustic chemical imaging, performing an in vivo chemical analysis that is spatially resolved (200 μm) and in real time, to predict a given tumor's...