Aleksandra Hac
Overview
Explore the profile of Aleksandra Hac including associated specialties, affiliations and a list of published articles.
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16
Citations
1274
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Recent Articles
1.
Brokowska J, Herman-Antosiewicz A, Hac A
Eur J Nutr
. 2024 Dec;
64(1):46.
PMID: 39680190
Purpose: Autophagy is a degradation process whose activation underlies beneficial effects of caloric restriction. Isothiocyanates (ITCs) induce autophagy in cancer cells, however, their impact on primary cells remains insufficiently explored,...
2.
Gimla M, Pyrczak-Felczykowska A, Malinowska M, Hac A, Narajczyk M, Bylinska I, et al.
Cancer Cell Int
. 2023 Sep;
23(1):210.
PMID: 37743482
Background: Pancreatic cancer is one of the leading causes of cancer death in Western societies. Its late diagnosis and resistance to chemotherapies result in a high mortality rate; thus, the...
3.
Stachurski O, Neubauer D, Walewska A, Ilowska E, Bauer M, Bartoszewska S, et al.
Antibiotics (Basel)
. 2022 Nov;
11(11).
PMID: 36358146
This study investigates short cationic antimicrobial lipopeptides composed of 2-4 amino acid residues and C-C fatty acids attached to the N-terminal part of the peptides. The findings were discussed in...
4.
Pyrczak-Felczykowska A, Reekie T, Jakalski M, Hac A, Malinowska M, Pawlik A, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163724
Derivatives of usnic acid (UA), a secondary metabolite from lichens, were synthesized to improve its anticancer activity and selectivity. Recently we reported the synthesis and activity of an UA isoxazole...
5.
Zdrowowicz M, Spisz P, Hac A, Herman-Antosiewicz A, Rak J
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163354
Radiotherapy is a crucial cancer treatment, but its outcome is still far from satisfactory. One of the reasons that cancer cells show resistance to ionizing radiation is hypoxia, defined as...
6.
Hac A, Pierzynowska K, Herman-Antosiewicz A
Cells
. 2021 Apr;
10(4).
PMID: 33920542
Autophagy is a specific macromolecule and organelle degradation process. The target macromolecule or organelle is first enclosed in an autophagosome, and then delivered along acetylated microtubules to the lysosome. Autophagy...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Maluch I, Stachurski O, Kosikowska-Adamus P, Makowska M, Bauer M, Wyrzykowski D, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33255674
Antimicrobial peptides (AMPs) constitute a promising tool in the development of novel therapeutic agents useful in a wide range of bacterial and fungal infections. Among the modifications improving pharmacokinetic and...
9.
Sawicka J, Dzierzynska M, Wardowska A, Deptula M, Rogujski P, Sosnowski P, et al.
Molecules
. 2020 Jun;
25(12).
PMID: 32585846
Regeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these...
10.
Pyrczak-Felczykowska A, Narlawar R, Pawlik A, Guzow-Krzeminska B, Artymiuk D, Hac A, et al.
J Nat Prod
. 2020 Feb;
83(2):563-564.
PMID: 32065747
No abstract available.