Aleksandr A Rubel
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Explore the profile of Aleksandr A Rubel including associated specialties, affiliations and a list of published articles.
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23
Citations
182
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Recent Articles
1.
Kachkin D, Zelinsky A, Romanova N, Kulichikhin K, Zykin P, Khorolskaya J, et al.
Int J Mol Sci
. 2025 Feb;
26(4).
PMID: 40003978
The formation of self-perpetuating protein aggregates such as amyloids is associated with various diseases and provides a basis for transmissible (infectious or heritable) protein isoforms (prions). Many human proteins involved...
2.
Grizel A, Gorsheneva N, Stevenson J, Pflaum J, Wilfling F, Rubel A, et al.
J Biol Chem
. 2024 Sep;
300(10):107766.
PMID: 39276934
Liquid protein condensates produced by phase separation are involved in the spatiotemporal control of cellular functions, while solid fibrous aggregates (amyloids) are associated with diseases and/or manifest as infectious or...
3.
Zdravkova K, Mijanovic O, Brankovic A, Ilicheva P, Jakovleva A, Karanovic J, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891048
Cysteine cathepsins F and W are members of the papain-like cysteine protease family, which have distinct structural features and functional roles in various physiological and pathological processes. This review provides...
4.
Nedorezova D, Rubel M, Rubel A
Biochemistry (Mosc)
. 2024 Apr;
89(Suppl 1):S249-S261.
PMID: 38621754
Nucleic acids (NAs) are important components of living organisms responsible for the storage and transmission of hereditary information. They form complex structures that can self-assemble and bind to various biological...
5.
Gorsheneva N, Sopova J, Azarov V, Grizel A, Rubel A
Biochemistry (Mosc)
. 2024 Apr;
89(Suppl 1):S205-S223.
PMID: 38621751
The term "biomolecular condensates" is used to describe membraneless compartments in eukaryotic cells, accumulating proteins and nucleic acids. Biomolecular condensates are formed as a result of liquid-liquid phase separation (LLPS)....
6.
Shumega A, Pavlov Y, Chirinskaite A, Rubel A, Inge-Vechtomov S, Stepchenkova E
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255897
The discovery of the CRISPR/Cas9 microbial adaptive immune system has revolutionized the field of genetics, by greatly enhancing the capacity for genome editing. CRISPR/Cas9-based editing starts with DNA breaks (or...
7.
Fedotov S, Khrabrova M, Vashukova E, Glotov A, Anpilova A, Dobronravov V, et al.
PLoS One
. 2024 Jan;
19(1):e0297144.
PMID: 38241324
Preeclampsia is a disorder that can occur during pregnancy and is one of the leading causes of death among pregnant women. This disorder occurs after the 20th week of pregnancy...
8.
Kulichikhin K, Malikova O, Zobnina A, Zalutskaya N, Rubel A
Life (Basel)
. 2023 Oct;
13(10).
PMID: 37895336
Proteinopathy is characterized by the accumulation of aggregates of a specific protein in a target organ, tissue, or cell. The aggregation of the same protein can cause different pathologies as...
9.
Kachkin D, Lashkul V, Gorsheneva N, Fedotov S, Rubel M, Chernoff Y, et al.
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762425
Numerous studies have demonstrated that people with type 2 diabetes mellitus (associated with IAPP peptide aggregation) show an increased incidence of Alzheimer's disease (associated with Aβ aggregation), but the mechanism...
10.
Rubel M, Shkodenko L, Gorbenko D, Solyanikova V, Maltzeva Y, Rubel A, et al.
Methods Mol Biol
. 2023 Aug;
2709:287-298.
PMID: 37572289
Structural RNA is a challenging target for recognition by hybridization probes. This chapter addresses the recognition problem of RNA amplicons in samples obtained by multiplex nucleic acid sequence-based amplification (NASBA)....