Aleksander Baldys
Overview
Explore the profile of Aleksander Baldys including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
304
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Recent Articles
1.
Roche J, Nasarre P, Gemmill R, Baldys A, Pontis J, Korch C, et al.
Cancers (Basel)
. 2016 Dec;
8(12).
PMID: 27983677
n/a.
2.
Copik A, Baldys A, Nguyen K, Sahdeo S, Ho H, Kosaka A, et al.
PLoS One
. 2015 Jan;
10(1):e0115701.
PMID: 25606852
The α1A-AR is thought to couple predominantly to the Gαq/PLC pathway and lead to phosphoinositide hydrolysis and calcium mobilization, although certain agonists acting at this receptor have been reported to...
3.
Liu M, Idkowiak-Baldys J, Roddy P, Baldys A, Raymond J, Clarke C, et al.
PLoS One
. 2013 Nov;
8(11):e80721.
PMID: 24244711
It is well established that acute activation of members of the protein kinase C (PKC) family induced by activation of cellular receptors can transduce extracellular stimuli to intracellular signaling. However,...
4.
Roche J, Nasarre P, Gemmill R, Baldys A, Pontis J, Korch C, et al.
Cancers (Basel)
. 2013 Nov;
5(2):334-56.
PMID: 24216980
The epithelial to mesenchymal transition (EMT) enables epithelial cells with a migratory mesenchymal phenotype. It is activated in cancer cells and is involved in invasion, metastasis and stem-like properties. ZEB1,...
5.
Zhang Z, Chu W, Song B, Gooz M, Zhang J, Yu C, et al.
PLoS One
. 2013 Aug;
8(8):e73424.
PMID: 23977387
Objective: Regulation of apical calcium entry is important for the function of principal cells of the collecting duct. However, the molecular identity and the regulators of the transporter/channel, which is...
6.
Baldys A, Raymond J
J Biol Chem
. 2011 Apr;
286(28):24656-65.
PMID: 21464131
The 5-hydroxytryptamine 2A receptor (5-HT(2A)R) undergoes constitutive and agonist-dependent internalization. Despite many advances in our understanding of G protein-coupled receptor trafficking, the exact mechanism of endocytic sorting of G protein-coupled...
7.
Tholanikunnel B, Joseph K, Kandasamy K, Baldys A, Raymond J, Luttrell L, et al.
J Biol Chem
. 2010 Aug;
285(44):33816-25.
PMID: 20739277
β(2)-adrenergic receptors (β(2)-AR) are low abundance, integral membrane proteins that mediate the effects of catecholamines at the cell surface. Whereas the processes governing desensitization of activated β(2)-ARs and their subsequent...
8.
Dey M, Baldys A, Sumter D, Gooz P, Luttrell L, Raymond J, et al.
J Pharmacol Exp Ther
. 2010 Jun;
334(3):775-83.
PMID: 20566668
Recent data show that increases in bradykinin (BK) concentration contribute to the beneficial effects of angiotensin-converting enzyme inhibitor (ACEI) treatment in chronic kidney disease. However, the possible role of BK...
9.
Baldys A, Raymond J
Biochemistry
. 2009 Aug;
48(40):9321-3.
PMID: 19673488
The molecular mechanisms of EGFR vesicular trafficking to lysosomes have recently received considerable attention. It is now clear that endosomal sorting complexes required for transport (ESCRTs) are critical for EGFR...
10.
Idkowiak-Baldys J, Baldys A, Raymond J, Hannun Y
J Biol Chem
. 2009 Jun;
284(33):22322-22331.
PMID: 19525236
Considerable insight has been garnered on initial mechanisms of endocytosis of plasma membrane proteins and their subsequent trafficking through the endosomal compartment. It is also well established that ligand stimulation...