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Aleksandar Poleksic

Explore the profile of Aleksandar Poleksic including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Poleksic A
IEEE/ACM Trans Comput Biol Bioinform . 2013 May; 10(1):226-9. PMID: 23702560
The Largest Common Point-set (LCP) and the Pattern Matching (PM) problems have received much attention in the fields of pattern matching, computer vision and computational biology. Perhaps, the most important...
12.
Arriagada M, Poleksic A
Biomed Res Int . 2013 Mar; 2013:459248. PMID: 23509725
The importance of pairwise protein structural comparison in biomedical research is fueling the search for algorithms capable of finding more accurate structural match of two input proteins in a timely...
13.
Poleksic A
IEEE/ACM Trans Comput Biol Bioinform . 2011 Oct; 9(2):511-6. PMID: 22025757
We study the well known LCP (Largest Common Point-Set) under Bottleneck Distance Problem. Given two proteins a and b (as sequences of points in 3D space) and a distance cutoff...
14.
Poleksic A
IEEE/ACM Trans Comput Biol Bioinform . 2011 Sep; 8(6):1716-20. PMID: 21904019
Protein structure alignment is an important tool in many biological applications, such as protein evolution studies, protein structure modeling, and structure-based, computer-aided drug design. Protein structure alignment is also one...
15.
Poleksic A
J Bioinform Comput Biol . 2011 Jun; 9(3):367-82. PMID: 21714130
The problem of finding an optimal structural alignment for a pair of superimposed proteins is often amenable to the Smith-Waterman dynamic programming algorithm, which runs in time proportional to the...
16.
Poleksic A
Bioinformatics . 2009 Sep; 25(21):2751-6. PMID: 19734152
Motivation: Structural alignment is an important tool for understanding the evolutionary relationships between proteins. However, finding the best pairwise structural alignment is difficult, due to the infinite number of possible...
17.
Poleksic A
BMC Bioinformatics . 2009 Apr; 10:112. PMID: 19379500
Background: In the last decade, a significant improvement in detecting remote similarity between protein sequences has been made by utilizing alignment profiles in place of amino-acid strings. Unfortunately, no analytical...
18.
Poleksic A, Fienup M, Danzer J, Debe D
J Bioinform Comput Biol . 2008 May; 6(2):335-45. PMID: 18464326
Measuring the accuracy of protein three-dimensional structures is one of the most important problems in protein structure prediction. For structure-based drug design, the accuracy of the binding site is far...
19.
Poleksic A, Fienup M
Bioinformatics . 2008 Mar; 24(9):1145-53. PMID: 18337259
Motivation: Profile-based protein homology detection algorithms are valuable tools in genome annotation and protein classification. By utilizing information present in the sequences of homologous proteins, profile-based methods are often able...
20.
Poleksic A, Danzer J, Palmer B, Olafson B, Debe D
Proteins . 2006 Sep; 65(4):953-8. PMID: 17006949
We present a novel, knowledge-based method for the side-chain addition step in protein structure modeling. The foundation of the method is a conditional probability equation, which specifies the probability that...