Alejandro A Granados
Overview
Explore the profile of Alejandro A Granados including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
483
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0
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Recent Articles
1.
Granados A, Kanrar N, Elowitz M
Cell Genom
. 2024 Jan;
4(1):100463.
PMID: 38216284
In animal cells, molecular pathways often comprise families of variant components, such as ligands or receptors. These pathway components are differentially expressed by different cell types, potentially tailoring pathway function...
2.
Xie Y, Reid C, Granados A, Turrero Garcia M, Dale-Huang F, Hanson S, et al.
bioRxiv
. 2023 Oct;
PMID: 37873089
Astrocyte specification during development is influenced by both intrinsic and extrinsic factors, but the precise contribution of each remains poorly understood. Here we show that septal astrocytes from Nkx2.1 and...
3.
Granados A, Bucher S, Song H, Agrawal A, Chen A, Peng T, et al.
Elife
. 2023 Oct;
12.
PMID: 37830426
Background: Infection by coronavirus SARS-CoV2 is a severe and often deadly disease that has implications for the respiratory system and multiple organs across the human body. While the effects in...
4.
Jones R, Karkanias J, Krasnow M, Pisco A, Quake S, Salzman J, et al.
Science
. 2022 May;
376(6594):eabl4896.
PMID: 35549404
Molecular characterization of cell types using single-cell transcriptome sequencing is revolutionizing cell biology and enabling new insights into the physiology of human organs. We created a human reference atlas comprising...
5.
Gong W, Granados A, Hu J, Jones M, Raz O, Salvador-Martinez I, et al.
Cell Syst
. 2021 Jun;
12(8):810-826.e4.
PMID: 34146472
The recent advent of CRISPR and other molecular tools enabled the reconstruction of cell lineages based on induced DNA mutations and promises to solve the ones of more complex organisms....
6.
Chow K, Budde M, Granados A, Cabrera M, Yoon S, Cho S, et al.
Science
. 2021 Apr;
372(6538).
PMID: 33833095
During multicellular development, spatial position and lineage history play powerful roles in controlling cell fate decisions. Using a serine integrase-based recording system, we engineered cells to record lineage information in...
7.
Granados A, Pietsch J, Cepeda-Humerez S, Farquhar I, Tkacik G, Swain P
Proc Natl Acad Sci U S A
. 2018 May;
115(23):6088-6093.
PMID: 29784812
Although cells respond specifically to environments, how environmental identity is encoded intracellularly is not understood. Here, we study this organization of information in budding yeast by estimating the mutual information...
8.
Granados A, Crane M, Montano-Gutierrez L, Tanaka R, Voliotis M, Swain P
Elife
. 2017 May;
6.
PMID: 28513433
Improving in one aspect of a task can undermine performance in another, but how such opposing demands play out in single cells and impact on fitness is mostly unknown. Here...