Alejandra R Alvarez
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Explore the profile of Alejandra R Alvarez including associated specialties, affiliations and a list of published articles.
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41
Citations
965
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Recent Articles
1.
Jara-Guajardo P, Morales-Zavala F, Bolanos K, Giralt E, Araya E, Acosta G, et al.
Int J Nanomedicine
. 2024 Jan;
18:8169-8185.
PMID: 38169997
Introduction: The development of new materials and tools for radiology is key to the implementation of this diagnostic technique in clinics. In this work, we evaluated the differential accumulation of...
2.
Martinez A, Lamaizon C, Valls C, Llambi F, Leal N, Fitzgerald P, et al.
Antioxidants (Basel)
. 2023 Nov;
12(11).
PMID: 38001860
The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however,...
3.
Marin T, Valls C, Jerez C, Huerta T, Elgueta D, Vidal R, et al.
IBRO Neurosci Rep
. 2023 Jan;
13:378-387.
PMID: 36590096
Parkinson's disease is the second most common neurodegenerative disorder. Although it is clear that dopaminergic neurons degenerate, the underlying molecular mechanisms are still unknown, and thus, successful treatment is still...
4.
Picon-Pages P, Fanlo-Ucar H, Herrera-Fernandez V, Auselle-Bosch S, Galera-Lopez L, Gutierrez D, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499491
Alzheimer's disease (AD) is characterised by the presence of extracellular amyloid plaques in the brain. They are composed of aggregated amyloid beta-peptide (Aβ) misfolded into beta-sheets which are the cause...
5.
Arevalo N, Lamaizon C, Cavieres V, Burgos P, Alvarez A, Yanez M, et al.
Front Mol Neurosci
. 2022 Aug;
15:934820.
PMID: 35992201
Gaucher disease (GD) is an inherited disorder caused by recessive mutations in the gene that encodes the lysosomal enzyme β-glucocerebrosidase (β-GC). β-GC hydrolyzes glucosylceramide (GluCer) into glucose and ceramide in...
6.
Gutierrez D, Chandia-Cristi A, Yanez M, Zanlungo S, Alvarez A
Neural Regen Res
. 2022 Jul;
18(2):237-243.
PMID: 35900397
Our ability to learn and remember depends on the active formation, remodeling, and elimination of synapses. Thus, the development and growth of synapses as well as their weakening and elimination...
7.
Marin T, Dulcey A, Campos F, de la Fuente C, Acuna M, Castro J, et al.
Front Cell Dev Biol
. 2022 Apr;
10:844297.
PMID: 35399514
Niemann-Pick type A (NPA) disease is a fatal lysosomal neurodegenerative disorder caused by the deficiency in acid sphingomyelinase (ASM) activity. NPA patients present severe and progressive neurodegeneration starting at an...
8.
Balboa E, Marin T, Oyarzun J, Contreras P, Hardt R, van den Bosch T, et al.
Cells
. 2021 Aug;
10(8).
PMID: 34440927
Niemann-Pick type C disease (NPCD) is a lysosomal storage disorder caused by mutations in the gene. The most affected tissues are the central nervous system and liver, and while significant...
9.
Gonzalez-Martin A, Moyano T, Gutierrez D, Carvajal F, Cerpa W, Hanley J, et al.
Prog Neurobiol
. 2021 Jul;
205:102122.
PMID: 34284000
Memory consolidation requires activation of a gene expression program that allows de novo protein synthesis. But the molecular mechanisms that favour or restrict that program are poorly understood. The kinase...
10.
Montecino F, Gonzalez N, Blanco N, Ramirez M, Gonzalez-Martin A, Alvarez A, et al.
Front Cell Dev Biol
. 2021 Mar;
9:606403.
PMID: 33777928
Satellite cells (SCs) are tissue-specific stem cells responsible for adult skeletal muscle regeneration and maintenance. SCs function is critically dependent on two families of transcription factors: the paired box (Pax)...