Alberto Pugliese
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Explore the profile of Alberto Pugliese including associated specialties, affiliations and a list of published articles.
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Articles
121
Citations
3543
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Recent Articles
11.
Zhao L, Papadopoulos G, Skyler J, Pugliese A, Parikh H, Kwok W, et al.
Diabetes Care
. 2024 Mar;
47(5):826-834.
PMID: 38498185
Objective: To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D). Research Design And Methods: Next-generation targeted...
12.
Burke G, Mitrofanova A, Fontanella A, Vendrame F, Ciancio G, Vianna R, et al.
Front Immunol
. 2024 Mar;
15:1354101.
PMID: 38495894
Beyond the direct benefit that a transplanted organ provides to an individual recipient, the study of the transplant process has the potential to create a better understanding of the pathogenesis,...
13.
Vecchio F, Carre A, Korenkov D, Zhou Z, Apaolaza P, Tuomela S, et al.
Sci Adv
. 2024 Mar;
10(10):eadl1122.
PMID: 38446892
Coxsackievirus B (CVB) infection of pancreatic β cells is associated with β cell autoimmunity and type 1 diabetes. We investigated how CVB affects human β cells and anti-CVB T cell...
14.
Liu H, Geravandi S, Grasso A, Sikdar S, Pugliese A, Maedler K
Front Endocrinol (Lausanne)
. 2023 Nov;
14:1236574.
PMID: 38027145
Introduction: For more than a century, enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D). Uncontrolled viral response pathways repeatedly presented during childhood highly correlate with autoimmunity...
15.
Doke M, Alvarez-Cubela S, Klein D, Altilio I, Schulz J, Mateus Goncalves L, et al.
Cell Metab
. 2023 Oct;
35(11):1944-1960.e7.
PMID: 37898119
Human pancreatic plasticity is implied from multiple single-cell RNA sequencing (scRNA-seq) studies. However, these have been invariably based on static datasets from which fate trajectories can only be inferred using...
16.
Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, et al.
Res Sq
. 2023 Oct;
PMID: 37886513
Human islet antigen reactive CD4 + memory T cells (IAR T cells) from peripheral blood have been studied extensively for their role in the pathogenesis of autoimmune type 1 diabetes...
17.
Racine J, Misherghi A, Dwyer J, Maser R, Forte E, Bedard O, et al.
J Immunol
. 2023 Oct;
211(12):1792-1805.
PMID: 37877672
In an effort to improve HLA-"humanized" mouse models for type 1 diabetes (T1D) therapy development, we previously generated directly in the NOD strain CRISPR/Cas9-mediated deletions of various combinations of murine...
18.
Vecchio F, Carre A, Korenkov D, Zhou Z, Apaolaza P, Tuomela S, et al.
bioRxiv
. 2023 Sep;
PMID: 37662376
Coxsackievirus B (CVB) infection of pancreatic β cells is associated with β-cell autoimmunity. We investigated how CVB impacts human β cells and anti-CVB T-cell responses. β cells were efficiently infected...
19.
Leung S, Lenchik N, Mathews C, Pugliese A, McCarthy D, Le Bagge S, et al.
Sci Rep
. 2023 Aug;
13(1):12948.
PMID: 37558746
Hypoglycemia in type 1 diabetes associates with changes in the pancreatic islet α cells, where the receptor for advanced glycation end products (RAGE) is highly expressed. This study compared islet...
20.
Perry D, Shapiro M, Chamberlain S, Kusmartseva I, Chamala S, Balzano-Nogueira L, et al.
Sci Data
. 2023 May;
10(1):323.
PMID: 37237059
The Network for Pancreatic Organ donors with Diabetes (nPOD) is the largest biorepository of human pancreata and associated immune organs from donors with type 1 diabetes (T1D), maturity-onset diabetes of...