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Albert Mennone

Explore the profile of Albert Mennone including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 966
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Recent Articles
11.
Weerachayaphorn J, Luo Y, Mennone A, Soroka C, Harry K, Boyer J
J Hepatol . 2013 Aug; 60(1):160-6. PMID: 23978715
Background & Aims: Oltipraz (4-methyl-5(pyrazinyl-2)-1-2-dithiole-3-thione), a promising cancer preventive agent, has an antioxidative activity and ability to enhance glutathione biosynthesis, phase II detoxification enzymes and multidrug resistance-associated protein-mediated efflux transporters....
12.
Amaya M, Oliveira A, Guimaraes E, Casteluber M, Carvalho S, Andrade L, et al.
Hepatology . 2013 Jul; 59(1):274-83. PMID: 23839970
Unlabelled: Insulin's metabolic effects in the liver are widely appreciated, but insulin's ability to act as a hepatic mitogen is less well understood. Because the insulin receptor (IR) can traffic...
13.
Cai S, Lionarons D, Hagey L, Soroka C, Mennone A, Boyer J
Hepatology . 2012 Nov; 57(6):2418-26. PMID: 23175353
The sea lamprey (Petromyzon marinus) is a genetically programmed animal model for biliary atresia, as it loses its bile ducts and gallbladder during metamorphosis. However, in contrast to patients with...
14.
Weerachayaphorn J, Mennone A, Soroka C, Harry K, Hagey L, Kensler T, et al.
Am J Physiol Gastrointest Liver Physiol . 2012 Feb; 302(9):G925-36. PMID: 22345550
The transcription factor nuclear factor-E2-related factor 2 (Nrf2) is a key regulator for induction of hepatic detoxification and antioxidant mechanisms, as well as for certain hepatobiliary transporters. To examine the...
15.
Soroka C, Velazquez H, Mennone A, Ballatori N, Boyer J
Am J Physiol Gastrointest Liver Physiol . 2011 Jul; 301(3):G574-9. PMID: 21719738
Bile acid homeostasis is tightly maintained through interactions between the liver, intestine, and kidney. During cholestasis, the liver is incapable of properly clearing bile acids from the circulation, and alternative...
16.
He H, Mennone A, Boyer J, Cai S
Hepatology . 2011 Jan; 53(2):548-57. PMID: 21274875
Unlabelled: Cholestasis leads to liver cell death, fibrosis, cirrhosis, and eventually liver failure. Despite limited benefits, ursodeoxycholic acid (UDCA) is the only Food and Drug Administration-approved treatment for cholestatic disorders....
17.
Mennone A, Nathanson M
Gastrointest Endosc . 2010 Dec; 73(2):338-44. PMID: 21145055
Background: Confocal endomicroscopy enables histopathology of the GI lumen to be observed in vivo. Recent prototypes of a confocal miniprobe are thin enough to be introduced through a needle. Objective:...
18.
Loeser C, Robert M, Mennone A, Nathanson M, Jamidar P
J Clin Gastroenterol . 2010 Nov; 45(3):246-52. PMID: 21063210
Background And Aims: Current methods to diagnose malignant biliary strictures are of low sensitivity. Confocal endomicroscopy is a new approach that may improve the diagnosis of indeterminate biliary strictures. The...
19.
Mennone A, Soroka C, Harry K, Boyer J
Drug Metab Dispos . 2010 Jul; 38(10):1673-8. PMID: 20601550
Breast cancer resistance protein (Bcrp) is a member of the ATP-binding cassette membrane transporter family, which is expressed apically in liver, kidney, and intestine epithelium. Recent reports suggest that in...
20.
Cruz L, Guerra M, Kruglov E, Mennone A, Garcia C, Chen J, et al.
Hepatology . 2010 Jun; 52(1):327-37. PMID: 20578149
Unlabelled: Multidrug resistance associated protein 2 (Mrp2) is a canalicular transporter responsible for organic anion secretion into bile. Mrp2 activity is regulated by insertion into the plasma membrane; however, the...