Albert G Tsai
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Explore the profile of Albert G Tsai including associated specialties, affiliations and a list of published articles.
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25
Citations
766
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Recent Articles
1.
Kim Y, Calderon A, Favaro P, Glass D, Tsai A, Ho D, et al.
Nat Commun
. 2024 Jul;
15(1):5910.
PMID: 39003273
Lymphoid specification in human hematopoietic progenitors is not fully understood. To better associate lymphoid identity with protein-level cell features, we conduct a highly multiplexed single-cell proteomic screen on human bone...
2.
Piyadasa H, Oberlton B, Kong A, Fullaway C, Varra S, Sowers C, et al.
J Vis Exp
. 2023 Oct;
(199).
PMID: 37782085
Multiplexed ion beam imaging (MIBI) is a next-generation mass spectrometry-based microscopy technique that generates 40+ plex images of protein expression in histologic tissues, enabling detailed dissection of cellular phenotypes and...
3.
Amouzgar M, Glass D, Baskar R, Averbukh I, Kimmey S, Tsai A, et al.
Patterns (N Y)
. 2022 Aug;
3(8):100536.
PMID: 36033591
Single-cell technologies generate large, high-dimensional datasets encompassing a diversity of omics. Dimensionality reduction captures the structure and heterogeneity of the original dataset, creating low-dimensional visualizations that contribute to the human...
4.
Vivanco Gonzalez N, Oliveria J, Tebaykin D, Ivison G, Mukai K, Tsai M, et al.
STAR Protoc
. 2022 Apr;
3(2):101280.
PMID: 35434655
Granulocytes encompass diverse roles, from fighting off pathogens to regulating inflammatory processes in allergies. These roles are represented by distinct cellular phenotypes that we captured with mass cytometry (CyTOF). Our...
5.
Zhang H, Chien M, Hou Y, Shomali W, Brar R, Ho C, et al.
Blood Adv
. 2022 Apr;
7(1):190-194.
PMID: 35381066
Cyclic thrombocytopenia (CTP) is a rare disease of periodic platelet count oscillations. The pathogenesis of CTP remains elusive. To study the underlying pathophysiology and genetic and cellular associations with CTP,...
6.
Vivanco Gonzalez N, Oliveria J, Tebaykin D, Ivison G, Mukai K, Tsai M, et al.
iScience
. 2020 Nov;
23(11):101724.
PMID: 33205028
Basophils, the rarest granulocyte, play critical roles in parasite- and allergen-induced inflammation. We applied mass cytometry (CyTOF) to simultaneously asses 44 proteins to phenotype and functionally characterize neutrophils, eosinophils, and...
7.
Glass D, Tsai A, Oliveria J, Hartmann F, Kimmey S, Calderon A, et al.
Immunity
. 2020 Jul;
53(1):217-232.e5.
PMID: 32668225
B cells are capable of a wide range of effector functions including antibody secretion, antigen presentation, cytokine production, and generation of immunological memory. A consistent strategy for classifying human B...
8.
Tsai A, Glass D, Juntilla M, Hartmann F, Oak J, Fernandez-Pol S, et al.
Nat Med
. 2020 Mar;
26(3):408-417.
PMID: 32161403
The diagnosis of lymphomas and leukemias requires hematopathologists to integrate microscopically visible cellular morphology with antibody-identified cell surface molecule expression. To merge these into one high-throughput, highly multiplexed, single-cell assay,...
9.
Munoz-Gonzalez J, Jara-Acevedo M, Alvarez-Twose I, Merker J, Teodosio C, Hou Y, et al.
Blood Adv
. 2018 Oct;
2(21):2814-2828.
PMID: 30373888
Systemic mastocytosis (SM) is a highly heterogeneous disease with indolent and aggressive forms, with the mechanisms leading to malignant transformation still remaining to be elucidated. Here, we investigated the presence...
10.
Wang S, Hasserjian R, Tam W, Tsai A, Geyer J, George T, et al.
Haematologica
. 2017 May;
102(8):1352-1360.
PMID: 28495918
Chronic eosinophilic leukemia, not otherwise specified can be difficult to distinguish from idiopathic hypereosinophilic syndrome according to the current World Health Organization guideline. To examine whether the morphological features of...