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Albert D Windhorst

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Articles 253
Citations 4546
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Recent Articles
11.
Wondergem N, Miedema I, van de Ven R, Zwezerijnen G, de Graaf P, Karagozoglu K, et al.
J Immunother Cancer . 2024 Jul; 12(7). PMID: 39038919
Background: Addition of neoadjuvant immune checkpoint inhibition to standard-of-care interventions for locally advanced oral cancer could improve clinical outcome. Methods: In this study, 16 evaluable patients with stage III/IV oral...
12.
Badenhorst M, Windhorst A, Beaino W
Front Med (Lausanne) . 2024 Jun; 11:1401515. PMID: 38915766
Immunotherapy targeted to immune checkpoint inhibitors, such as the program cell death receptor (PD-1) and its ligand (PD-L1), has revolutionized cancer treatment. However, it is now well-known that PD-1/PD-L1 immunotherapy...
13.
Bonanno F, Saw R, Bleher D, Papadopoulos I, Bowden G, Bjerregaard-Andersen K, et al.
ACS Omega . 2024 Jun; 9(23):24774-24788. PMID: 38882134
The development of positron emission tomography (PET) tracers capable of detecting α-synuclein (α-syn) aggregates in vivo would represent a breakthrough for advancing the understanding and enabling the early diagnosis of...
14.
Veth L, Windhorst A, Vugts D
Chem Commun (Camb) . 2024 Jun; 60(53):6801-6804. PMID: 38869169
A method for the radiosynthesis of F-labelled aryl trifluoromethyl ketones starting from widely available Weinreb amides using [F]fluoroform is presented. The method uses potassium hexamethyldisilazane as base and delivers products...
15.
Scott A, Zeglis B, Lapi S, Scott P, Windhorst A, Abdel-Wahab M, et al.
Lancet Oncol . 2024 May; 25(6):e250-e259. PMID: 38821099
Although the promise of radionuclides for the diagnosis and treatment of disease was recognised soon after the discovery of radioactivity in the late 19th century, the systematic use of radionuclides...
16.
Lapi S, Scott P, Scott A, Windhorst A, Zeglis B, Abdel-Wahab M, et al.
Lancet Oncol . 2024 May; 25(6):e236-e249. PMID: 38821098
This paper is the first of a Series on theranostics that summarises the current landscape of the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we describe...
17.
Ruytenberg T, Ciggaar I, Peters I, Noortman W, Dibbets-Schneider P, de Muynck L, et al.
Mol Imaging Biol . 2024 May; 26(4):577-584. PMID: 38775919
Purpose: To describe the pharmacokinetic properties of the [F]fluoro-polyethylene glycol(PEG)-folate radiotracer in PET/CT imaging of patients with advanced stage epithelial ovarian cancer (EOC). Procedures: In five patients with advanced EOC...
18.
Veth L, Windhorst A, Vugts D
Angew Chem Int Ed Engl . 2024 Apr; 63(27):e202404278. PMID: 38656696
Positron emission tomography (PET) is becoming increasingly important in nuclear medicine and drug discovery. To date, the development of many potential PET tracers is hampered by the lack of suitable...
19.
Xia R, Shi S, Xu Z, Vischer H, Windhorst A, Qian Y, et al.
Nat Commun . 2024 Mar; 15(1):2493. PMID: 38509098
The histamine H receptor (HR) plays key role in immune cell function and is a highly valued target for treating allergic and inflammatory diseases. However, structural information of HR remains...
20.
Palard-Novello X, Visser D, Tolboom N, Smith C, Zwezerijnen G, van de Giessen E, et al.
EJNMMI Phys . 2024 Mar; 11(1):25. PMID: 38472680
Background: Accurate image-derived input function (IDIF) from highly sensitive large axial field of view (LAFOV) PET/CT scanners could avoid the need of invasive blood sampling for kinetic modelling. The aim...