Albert C Ludolph
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Explore the profile of Albert C Ludolph including associated specialties, affiliations and a list of published articles.
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585
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14998
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Recent Articles
1.
Wiesenfarth M, Forouhideh-Wiesenfarth Y, Elmas Z, Parlak O, Weiland U, Herrmann C, et al.
J Neurol
. 2025 Mar;
272(4):259.
PMID: 40056187
No abstract available.
2.
Guillot S, Lang C, Simonot M, Beckett D, Lule D, Balz L, et al.
Sci Transl Med
. 2025 Jan;
17(783):eadm7580.
PMID: 39879320
Sleep alterations have been described in several neurodegenerative diseases yet are currently poorly characterized in amyotrophic lateral sclerosis (ALS). This study investigates sleep macroarchitecture and related hypothalamic signaling disruptions in...
3.
Kassubek J, Roselli F, Witzel S, Dorst J, Ludolph A, Rasche V, et al.
Sci Rep
. 2025 Jan;
15(1):1551.
PMID: 39789167
Primary lateral sclerosis (PLS) is a motor neuron disease (MND) which mainly affects upper motor neurons. Within the MND spectrum, PLS is much more slowly progressive than amyotrophic laterals sclerosis...
4.
Mravinacova S, Bergstrom S, Olofsson J, de San Jose N, Anderl-Straub S, Diehl-Schmid J, et al.
Sci Rep
. 2025 Jan;
15(1):668.
PMID: 39753643
Accurate diagnosis and monitoring of neurodegenerative diseases require reliable biomarkers. Cerebrospinal fluid (CSF) proteins are promising candidates for reflecting brain pathology; however, their diagnostic utility may be compromised by natural...
5.
Spencer P, Berntsson S, Buguet A, Butterfield P, Calne D, Calne S, et al.
J Neurol Sci
. 2024 Dec;
468():123340.
PMID: 39667295
While rising global rates of neurodegenerative disease encourage early diagnosis and therapeutic intervention to block clinical expression (secondary prevention), a more powerful approach is to identify and remove environmental factors...
6.
Dash B, Freischmidt A, Helferich A, Ludolph A, Andersen P, Weishaupt J, et al.
Front Cell Neurosci
. 2024 Nov;
18:1457704.
PMID: 39588282
Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (MNs) present in the spinal cord, brain stem and motor cortex. Death in...
7.
Koch J, Leha A, Bidner H, Cordts I, Dorst J, GuNTHER R, et al.
Lancet Neurol
. 2024 Oct;
23(11):1133-1146.
PMID: 39424560
Background: Fasudil is a small molecule inhibitor of Rho-associated kinase (ROCK) and is approved for the treatment of subarachnoid haemorrhage. In preclinical studies, fasudil has been shown to attenuate neurodegeneration,...
8.
Borroni B, Tarantino B, Graff C, Kruger J, Ludolph A, Moreno F, et al.
Neurology
. 2024 Sep;
103(7):e209793.
PMID: 39226519
Background And Objectives: Data on care home admission and survival rates of patients with syndromes associated with frontotemporal lobar degeneration (FTLD) are limited. However, their estimation is essential to plan...
9.
Uzelac Z, Schwable B, Dorst J, Rosenbohm A, Wollinsky K, Wurster C, et al.
Ther Adv Neurol Disord
. 2024 Aug;
17:17562864241263420.
PMID: 39206217
Background: This prospective study investigates the pattern of pareses in 5q-associated spinal muscular atrophy (SMA) to identify disease-specific characteristics and potential differences from amyotrophic lateral sclerosis (ALS) and spinobulbar muscular...
10.
Witzel S, Huss A, Nagel G, Rosenbohm A, Rothenbacher D, Peter R, et al.
Ann Neurol
. 2024 Aug;
96(6):1040-1057.
PMID: 39177232
Objective: Neurofilament light chains (NfL) and phosphorylated neurofilament heavy chains (pNfH), established as diagnostic and prognostic biomarkers in hospital-based amyotrophic lateral sclerosis (ALS) cohorts, are now surrogate markers in clinical...