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Alan T Nguyen

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Articles 17
Citations 347
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Recent Articles
1.
Lad M, Beniwal A, Jain S, Shukla P, Kalistratova V, Jung J, et al.
Cancer Cell . 2024 Sep; 42(9):1549-1569.e16. PMID: 39255776
Tumor-associated neutrophil (TAN) effects on glioblastoma (GBM) biology remain under-characterized. We show here that neutrophils with dendritic features-including morphological complexity, expression of antigen presentation genes, and the ability to process...
2.
Michel M, Shahrestani S, Boyke A, Garcia C, Menaker S, Aguilera-Pena M, et al.
Clin Neurol Neurosurg . 2024 Sep; 246:108521. PMID: 39236416
Objective: The escalating healthcare expenditures in the United States, particularly in neurosurgery, necessitate effective tools for predicting patient outcomes and optimizing resource allocation. This study explores the utility of combining...
3.
Guo J, Lopez D, Mascharak S, Foster D, Khan A, Davitt M, et al.
Tissue Eng Part A . 2024 Jun; 30(19-20):605-613. PMID: 38874979
Pancreatic ductal adenocarcinoma (PDAC) represents one of the only cancers with an increasing incidence rate and is often associated with intra- and peri-tumoral scarring, referred to as desmoplasia. This scarring...
4.
Mascharak S, Guo J, Foster D, Khan A, Davitt M, Nguyen A, et al.
Cell Rep Med . 2023 Oct; 4(11):101248. PMID: 37865092
Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading cause of cancer-related death. Hallmarks include desmoplasia with variable extracellular matrix (ECM) architecture and a complex microenvironment with spatially...
5.
Lad B, Beniwal A, Jain S, Shukla P, Jung J, Shah S, et al.
bioRxiv . 2023 Mar; PMID: 36993266
Tumor-associated neutrophil (TAN) effects on glioblastoma biology remain under-characterized. We show here that 'hybrid' neutrophils with dendritic features - including morphological complexity, expression of antigen presentation genes, and the ability...
6.
Jain S, Rick J, Joshi R, Beniwal A, Spatz J, Gill S, et al.
J Clin Invest . 2023 Mar; 133(5). PMID: 36856115
Cancer-associated fibroblasts (CAFs) were presumed absent in glioblastoma given the lack of brain fibroblasts. Serial trypsinization of glioblastoma specimens yielded cells with CAF morphology and single-cell transcriptomic profiles based on...
7.
Foster D, Januszyk M, Delitto D, Yost K, Griffin M, Guo J, et al.
Cancer Cell . 2022 Oct; 40(11):1392-1406.e7. PMID: 36270275
Cancer-associated fibroblasts (CAFs) are integral to the solid tumor microenvironment. CAFs were once thought to be a relatively uniform population of matrix-producing cells, but single-cell RNA sequencing has revealed diverse...
8.
Nguyen A, Hemphill S, Donahue B, Menendez M, Rodriguez S, Caruso T
J Pediatr Rehabil Med . 2022 Sep; 16(2):415-423. PMID: 36120795
Virtual reality (VR) technology has seen increasing use in physical rehabilitation and in the management of acute and chronic pain. Functional movement disorders (FMDs) are a source of disability with...
9.
Safaee M, Wang E, Jain S, Chen J, Gill S, Zheng A, et al.
Sci Rep . 2022 Jan; 12(1):1464. PMID: 35087132
Glioblastoma (GBM) is the most common primary brain tumor with a median survival under two years. Using in silico and in vitro techniques, we demonstrate heterogeneous expression of CD97, a...
10.
Foster D, Januszyk M, Yost K, Chinta M, Gulati G, Nguyen A, et al.
Proc Natl Acad Sci U S A . 2021 Oct; 118(41). PMID: 34620713
In the skin, tissue injury results in fibrosis in the form of scars composed of dense extracellular matrix deposited by fibroblasts. The therapeutic goal of regenerative wound healing has remained...