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Alan John Slusarenko

Explore the profile of Alan John Slusarenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 136
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Recent Articles
1.
Mosbauer K, Fritsch V, Adrian L, Bernhardt J, Gruhlke M, Slusarenko A, et al.
Front Microbiol . 2021 Nov; 12:746795. PMID: 34777295
Allicin (diallyl thiosulfinate) is the major thiol-reactive organosulfur compound produced by garlic plants () upon tissue damage. Allicin exerts its strong antimicrobial activity against bacteria and fungi via -thioallylation of...
2.
Van Loi V, Busche T, Fritsch V, Weise C, Gruhlke M, Slusarenko A, et al.
Free Radic Biol Med . 2021 Oct; 177:120-131. PMID: 34678418
Staphylococcus aureus has to cope with oxidative and electrophile stress during host-pathogen interactions. The TetR-family repressor GbaA was shown to sense electrophiles, such as N-ethylmaleimide (NEM) via monothiol mechanisms of...
3.
Reiter J, Hubbers A, Albrecht F, Leichert L, Slusarenko A
Int J Med Microbiol . 2019 Oct; 310(1):151359. PMID: 31585716
Allicin (diallylthiosulfinate) is a potent antimicrobial substance, produced by garlic tissues upon wounding as a defence against pathogens and pests. Allicin is a reactive sulfur species (RSS) that oxidizes accessible...
4.
Van Loi V, Thu Huyen N, Busche T, Tung Q, Gruhlke M, Kalinowski J, et al.
Free Radic Biol Med . 2019 May; 139:55-69. PMID: 31121222
The prevalence of methicillin-resitant Staphylococcus aureus (MRSA) in hospitals and the community poses an increasing health burden, which requires the discovery of alternative antimicrobials. Allicin (diallyl thiosulfinate) from garlic exhibits...
5.
Muller A, Eller J, Albrecht F, Prochnow P, Kuhlmann K, Bandow J, et al.
J Biol Chem . 2016 Mar; 291(22):11477-90. PMID: 27008862
Allicin (diallyl thiosulfinate) from garlic is a highly potent natural antimicrobial substance. It inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains. However, the precise mode of action...