Alan H Lazarus
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Explore the profile of Alan H Lazarus including associated specialties, affiliations and a list of published articles.
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Articles
75
Citations
1178
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Recent Articles
11.
Cruz-Leal Y, Lazarus A
Transfusion
. 2021 Feb;
61(4):1004-1006.
PMID: 33624837
No abstract available.
12.
Norris P, Kaur G, Lazarus A
Curr Opin Hematol
. 2020 Sep;
27(6):392-398.
PMID: 32868670
Purpose Of Review: Intravenous immunoglobulin (IVIg) is an effective treatment for an increasing number of autoimmune and inflammatory conditions. However, IVIg continues to be limited by problems of potential shortages...
13.
Khan R, Menard M, Jen C, Chen X, Norris P, Lazarus A
Blood
. 2020 May;
135(26):2420-2424.
PMID: 32374819
Polyclonal anti-D is a first-line therapy for immune thrombocytopenia (ITP). Monoclonal antibodies are desirable alternatives, but none have yet proven successful despite their ability to opsonize erythrocytes (or red blood...
14.
Norris P, Segel G, Burack W, Sachs U, Lissenberg-Thunnissen S, Vidarsson G, et al.
Haematologica
. 2020 Feb;
106(1):250-254.
PMID: 32107327
No abstract available.
15.
Wabnitz H, Khan R, Lazarus A
Transfus Apher Sci
. 2020 Jan;
59(1):102710.
PMID: 31926738
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare neonatal disorder that is caused by alloimmunization against platelet antigens during pregnancy. Although rare, affecting only 1 in 1000 live births,...
16.
Crow A, Kapur R, Koernig S, Campbell I, Jen C, Mott P, et al.
Sci Transl Med
. 2019 Aug;
11(506).
PMID: 31434758
Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte...
17.
Vollenberg R, Jouni R, Norris P, Burg-Roderfeld M, Cooper N, Rummel M, et al.
Haematologica
. 2019 Mar;
104(6):1237-1243.
PMID: 30923095
Platelet autoantibody-induced platelet clearance represents a major pathomechanism in immune thrombocytopenia (ITP). There is growing evidence for clinical differences between anti-glycoprotein IIb/IIIa and anti-glycoprotein Ib/IX mediated ITP. Glycoprotein V is...
18.
Xu M, Li J, Dias Neves M, Zhu G, Carrim N, Yu R, et al.
Blood
. 2018 May;
132(6):622-634.
PMID: 29794068
Thrombopoietin (TPO), a hematopoietic growth factor produced predominantly by the liver, is essential for thrombopoiesis. Prevailing theory posits that circulating TPO levels are maintained through its clearance by platelets and...
19.
Sullivan H, Arthur C, Thompson L, Patel S, Stowell S, Hendrickson J, et al.
Transfusion
. 2018 Feb;
58(2):542-544.
PMID: 29411397
No abstract available.
20.
Cruz-Leal Y, Marjoram D, Lazarus A
J Immunol
. 2018 Jan;
200(4):1295-1305.
PMID: 29358275
Anti-D prevents hemolytic disease of the fetus and newborn, and this mechanism has been referred to as Ab-mediated immune suppression (AMIS). Anti-D, as well as other polyclonal AMIS-inducing Abs, most...