Alaa Amash
Overview
Explore the profile of Alaa Amash including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
208
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Recent Articles
1.
Amash A, Volkers G, Farber P, Griffin D, Davison K, Goodman A, et al.
MAbs
. 2024 Aug;
16(1):2394229.
PMID: 39189686
Bispecific antibodies (bsAb) and multispecific antibodies (msAb) encompass a diverse variety of formats that can concurrently bind multiple epitopes, unlocking mechanisms to address previously difficult-to-treat or incurable diseases. Early assessment...
2.
Crow A, Kapur R, Koernig S, Campbell I, Jen C, Mott P, et al.
Sci Transl Med
. 2019 Aug;
11(506).
PMID: 31434758
Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte...
3.
Zaid H, Silbermann M, Amash A, Gincel D, Abdel-Sattar E, Sarikahya N
Evid Based Complement Alternat Med
. 2017 May;
2017:7952417.
PMID: 28491112
No abstract available.
4.
Bernardo L, Amash A, Marjoram D, Lazarus A
Blood
. 2016 Jun;
128(8):1076-80.
PMID: 27330002
Although the prevention of hemolytic disease of the fetus and newborn is highly effective using polyclonal anti-D, a recombinant alternative is long overdue. Unfortunately, anti-D monoclonal antibodies have been, at...
5.
Amash A, Wang L, Wang Y, Bhakta V, Fairn G, Hou M, et al.
J Immunol
. 2016 Mar;
196(8):3331-40.
PMID: 26944929
Targeting CD44, a major leukocyte adhesion molecule, using specific Abs has been shown beneficial in several models of autoimmune and inflammatory diseases. The mechanisms contributing to the anti-inflammatory effects of...
6.
Bernardo L, Yu H, Amash A, Zimring J, Lazarus A
J Immunol
. 2015 Jul;
195(5):2224-30.
PMID: 26188060
Polyclonal anti-D has been used to prevent RhD-negative mothers from becoming immunized against RhD positive fetal erythrocytes, and this mechanism has been referred as Ab or IgG-mediated immune suppression (AMIS)....
7.
Crow A, Amash A, Lazarus A
Transfusion
. 2014 Dec;
55(6 Pt 2):1492-500.
PMID: 25496771
Background: Several monoclonal antibodies to CD44 can successfully ameliorate murine immune thrombocytopenia (ITP). As these antibodies may be a potential replacement for intravenous immune globulin (IVIG) in the treatment of...
8.
Yu H, Stowell S, Bernardo L, Hendrickson J, Zimring J, Amash A, et al.
J Immunol
. 2014 Aug;
193(6):2902-10.
PMID: 25122924
Anti-D can prevent immunization to the RhD Ag on RBCs, a phenomenon commonly termed Ab-mediated immune suppression (AMIS). The most accepted theory to explain this effect has been the rapid...
9.
Weintraub A, Amash A, Eshkoli T, Piltcher Haber E, Bronfenmacher B, Sheiner E, et al.
Hypertens Pregnancy
. 2013 Jun;
32(2):178-88.
PMID: 23725083
Objective: To evaluate the effect of magnesium sulfate (MgSO(4)) on placental expression levels of vascular endothelial growth factor (VEGF). Materials And Methods: Cotyledons of term normotensive and preeclamptic placentas were...
10.
Eshkoli T, Holcberg G, Bronfenmacher B, Amash A, Huleihel M, Erez O
J Matern Fetal Neonatal Med
. 2012 Aug;
26(2):116-22.
PMID: 22928533
Objective: To examine the effect of magnesium sulfate (MgSO(4)) on sFlt (soluble fms-like tyrosine kinase)-1 in the fetal and maternal compartments of normotensive and preeclamptic placentas. Methods: Cotyledons of term...