Alan H Handyside
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Explore the profile of Alan H Handyside including associated specialties, affiliations and a list of published articles.
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50
Citations
1264
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Recent Articles
1.
Tutt D, Guven-Ates G, Kwong W, Simmons R, Sang F, Silvestri G, et al.
Front Endocrinol (Lausanne)
. 2023 Nov;
14:1280847.
PMID: 38027209
Background: maturation (IVM) of germinal vesicle intact oocytes prior to fertilization (IVF) is practiced widely in animals. In human assisted reproduction it is generally reserved for fertility preservation or where...
2.
McCoy R, Summers M, McCollin A, Ottolini C, Ahuja K, Handyside A
Genome Med
. 2023 Oct;
15(1):77.
PMID: 37779206
Background: The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and stillbirth following...
3.
Jochems R, Canedo-Ribeiro C, Silvestri G, Derks M, Hamland H, Zak L, et al.
Cells
. 2023 Mar;
12(5).
PMID: 36899925
Preimplantation genetic testing for aneuploidy (PGT-A) is widespread, but controversial, in humans and improves pregnancy and live birth rates in cattle. In pigs, it presents a possible solution to improve...
4.
Silvestri G, Canedo-Ribeiro C, Serrano-Albal M, Labrecque R, Blondin P, Larmer S, et al.
Cells
. 2021 Sep;
10(9).
PMID: 34571932
Approximately one million in vitro produced (IVP) cattle embryos are transferred worldwide each year as a way to improve the rates of genetic gain. The most advanced programmes also apply...
5.
Handyside A, McCollin A, Summers M, Ottolini C
Prenat Diagn
. 2020 Aug;
41(5):525-535.
PMID: 32833230
Preimplantation genetic testing for aneuploidy (PGT-A) by copy number analysis is now widely used to select euploid embryos for transfer. Whole or partial chromosome aneuploidy can arise in meiosis, predominantly...
6.
Munne S, Kaplan B, Frattarelli J, Child T, Nakhuda G, Shamma F, et al.
Fertil Steril
. 2019 Sep;
112(6):1071-1079.e7.
PMID: 31551155
Objective: To evaluate the benefit of next-generation sequencing (NGS)-based preimplantation genetic testing for aneuploidy (PGT-A) for embryo selection in frozen-thawed embryo transfer. Design: Randomized controlled trial. Setting: Not applicable. Patient(s):...
7.
McCollin A, Swann R, Summers M, Handyside A, Ottolini C
Eur J Med Genet
. 2019 Apr;
63(2):103651.
PMID: 30995534
Despite improvements in culture conditions and laboratory techniques still only about 50% of human embryos reach the blastocyst stage of development in vitro. While many factors influence embryo development, aberrant...
8.
Turner K, Silvestri G, Black D, Dobson G, Smith C, Handyside A, et al.
Theriogenology
. 2018 Nov;
125:249-258.
PMID: 30476758
In cattle breeding, the development of genomic selection strategies based on single nucleotide polymorphism (SNP) interrogation has led to improved rates of genetic gain. Additionally, the application of genomic selection...
9.
Rosenwaks Z, Handyside A, Fiorentino F, Gleicher N, Paulson R, Schattman G, et al.
Fertil Steril
. 2018 Aug;
110(3):353-361.
PMID: 30098682
No abstract available.
10.
Rosenwaks Z, Handyside A
Fertil Steril
. 2018 Aug;
110(3):351-352.
PMID: 30098681
No abstract available.