Alan C Whitmore
Overview
Explore the profile of Alan C Whitmore including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1287
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0
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Recent Articles
1.
Hampton B, Plante K, Whitmore A, Linnertz C, Madden E, Noll K, et al.
PLoS Genet
. 2022 Dec;
18(12):e1010548.
PMID: 36574452
Variation in immune homeostasis, the state in which the immune system is maintained in the absence of stimulation, is highly variable across populations. This variation is attributed to both genetic...
2.
Noll K, Whitmore A, West A, McCarthy M, Morrison C, Plante K, et al.
Cell Rep
. 2020 Apr;
31(4):107587.
PMID: 32348764
Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse genetic reference...
3.
Gunn B, Jones J, Shabman R, Whitmore A, Sarkar S, Blevins L, et al.
Virology
. 2018 Jan;
515:250-260.
PMID: 29324290
Mannose binding lectin (MBL) generally plays a protective role during viral infection, yet MBL-mediated complement activation promotes Ross River virus (RRV)-induced inflammatory tissue destruction, contributing to arthritis and myositis. As...
4.
Maurizio P, Ferris M, Keele G, Miller D, Shaw G, Whitmore A, et al.
G3 (Bethesda)
. 2017 Dec;
8(2):427-445.
PMID: 29187420
Influenza A virus (IAV) is a respiratory pathogen that causes substantial morbidity and mortality during both seasonal and pandemic outbreaks. Infection outcomes in unexposed populations are affected by host genetics,...
5.
Jones J, Long K, Whitmore A, Sanders W, Thurlow L, Brown J, et al.
mBio
. 2017 Nov;
8(6).
PMID: 29138302
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in...
6.
Long K, Ferris M, Whitmore A, Montgomery S, Thurlow L, McGee C, et al.
J Virol
. 2015 Oct;
90(1):433-43.
PMID: 26491151
Unlabelled: Chikungunya virus (CHIKV) is an alphavirus responsible for causing epidemic outbreaks of polyarthralgia in humans. Because CHIKV is initially introduced via the skin, where γδ T cells are prevalent,...
7.
Gralinski L, Ferris M, Aylor D, Whitmore A, Green R, Frieman M, et al.
PLoS Genet
. 2015 Oct;
11(10):e1005504.
PMID: 26452100
New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross...
8.
Donohoe D, Holley D, Collins L, Montgomery S, Whitmore A, Hillhouse A, et al.
Cancer Discov
. 2014 Oct;
4(12):1387-97.
PMID: 25266735
Unlabelled: Whether dietary fiber protects against colorectal cancer is controversial because of conflicting results from human epidemiologic studies. However, these studies and mouse models of colorectal cancer have not controlled...
9.
Xiong H, Morrison J, Ferris M, Gralinski L, Whitmore A, Green R, et al.
G3 (Bethesda)
. 2014 Jun;
4(8):1429-44.
PMID: 24902603
Genetic variation between diverse mouse species is well-characterized, yet existing knowledge of the mouse transcriptome comes largely from one mouse strain (C57BL/6J). As such, it is unlikely to reflect the...
10.
Long K, Whitmore A, Ferris M, Sempowski G, McGee C, Trollinger B, et al.
J Virol
. 2013 Mar;
87(10):5697-706.
PMID: 23487448
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for recent epidemic outbreaks of debilitating disease in humans. Alphaviruses are known to interact with members of the C-type lectin receptor family...