Alaa M Hayallah
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Explore the profile of Alaa M Hayallah including associated specialties, affiliations and a list of published articles.
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37
Citations
526
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Recent Articles
11.
Hassan H, Allam A, Abu-Baih D, Mohamed M, Abdelmohsen U, Shimizu K, et al.
RSC Adv
. 2022 May;
10(60):36920-36929.
PMID: 35517980
Metabolic profiling of the crude methanolic extract of leaves has revealed the presence of different phenolic and nitrogenous compounds including cerebrosides and tetrapyrrole pigments. A phytochemical study of the ethyl...
12.
Abd El-Kader A, Khalaf Mahmoud B, Hajjar D, Mohamed M, Hayallah A, Abdelmohsen U
RSC Adv
. 2022 May;
10(38):22730-22741.
PMID: 35514559
A new triterpenoidal saponin identified as 3--[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 4)-β-d-xylopyranosyl]-2β,3β,16α-trihydroxyolean-12-en-23,28-dioic acid-28--α-l-rhamnopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 2)-α-l-arabinopyranoside 1 together with a new oleanane triterpene identified as 2β,3β,13α,22α-tetrahydroxy olean-23,28-dioic acid...
13.
Mekheimer R, Allam S, Al-Sheikh M, Moustafa M, Al-Mousawi S, Mostafa Y, et al.
Bioorg Chem
. 2022 Feb;
121:105693.
PMID: 35219045
A novel series of pyrimido[5,4-c]quinoline derivatives variously substituted at positions 2 and 5 have been synthesized, in good to excellent yields, via rapid base-catalyzed cyclization reaction of 2,4-dichloroquinoline-3-carbonitrile (5) with...
14.
Mohamed S, Abdelgawad M, Alaaeldin R, Fathalla Z, Moharram H, A Abdallah R, et al.
Pharmaceuticals (Basel)
. 2022 Jan;
15(1).
PMID: 35056101
Keratitis is a global health issue that claims the eye sight of millions of people every year. Dry eye, contact lens wearing and refractive surgeries are among the most common...
15.
Mustafa M, Abd El-Hafeez A, Abdelhafeez D, Abdelhamid D, Mostafa Y, Ghosh P, et al.
Future Med Chem
. 2021 Aug;
13(18):1559-1590.
PMID: 34340532
FAK, a nonreceptor tyrosine kinase, has been recognized as a novel target class for the development of targeted anticancer agents. Overexpression of FAK is a common occurrence in several solid...
16.
Shady N, Hayallah A, Mohamed M, Ghoneim M, Chilingaryan G, Al-Sanea M, et al.
Molecules
. 2021 Jul;
26(12).
PMID: 34205768
Since December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has caused tremendous economic loss and serious health problems worldwide. In this study, we investigated 14 natural compounds isolated from sp....
17.
Mustafa M, Abd El-Hafeez A, Abdelhamid D, Katkar G, Mostafa Y, Ghosh P, et al.
Eur J Med Chem
. 2021 Jun;
222:113569.
PMID: 34111829
Novel 5-pyridinyl-1,2,4-triazoles were designed as dual inhibitors of histone deacetylase 2 (HDAC2) and focal adhesion kinase (FAK). Compounds 5d, 6a, 7c, and 11c were determined as potential inhibitors of both...
18.
Abdelhafez O, Fahim J, Mustafa M, AboulMagd A, Desoukey S, Hayallah A, et al.
Nat Prod Res
. 2021 May;
36(11):2893-2896.
PMID: 34027770
The ongoing spread of SARS-CoV-2 has created a growing need to develop effective antiviral treatments; therefore, this work was undertaken to delve into the natural metabolites of the Red Sea...
19.
El-Hawary S, Issa M, Ebrahim H, Mohammed A, Hayallah A, El-Kadder E, et al.
Nat Prod Res
. 2021 May;
36(11):2843-2847.
PMID: 33949276
One of the promising therapeutic strategies for corona virus 2019 (COVID-19) is tolook for enzyme inhibitors. COVID-19 virus main protease (M) plays a vital role in mediating viral transcription and...
20.
Mustafa M, Abuo-Rahma G, Abd El-Hafeez A, Ahmed E, Abdelhamid D, Ghosh P, et al.
Bioorg Med Chem Lett
. 2021 Mar;
40:127965.
PMID: 33744442
Small molecule inhibitors of the focal adhesion kinase are regarded as promising tools in our armamentarium for treating cancer. Here, we identified four 1,2,4-triazole derivatives that inhibit FAK kinase significantly...