Akalabya Bissoyi
Overview
Explore the profile of Akalabya Bissoyi including associated specialties, affiliations and a list of published articles.
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37
Citations
308
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Recent Articles
1.
Gao Y, Bissoyi A, Guo Q, Gibson M
ACS Biomater Sci Eng
. 2024 Sep;
11(1):208-212.
PMID: 39315639
Spheroids and other 3D cellular models more accurately recapitulate physiological responses when compared to 2D models and represent potential alternatives to animal testing. The cryopreservation of spheroids remains challenging, limiting...
2.
Warren M, Biggs C, Bissoyi A, Gibson M, Sosso G
Nat Commun
. 2024 Sep;
15(1):8082.
PMID: 39278938
Controlling the formation and growth of ice is essential to successfully cryopreserve cells, tissues and biologics. Current efforts to identify materials capable of modulating ice growth are guided by iterative...
3.
Bissoyi A, Gao Y, Tomas R, Kinney N, Whale T, Guo Q, et al.
ACS Appl Mater Interfaces
. 2024 Apr;
PMID: 38671549
Cell-based models, such as organ-on-chips, can replace and inform in vivo (animal) studies for drug discovery, toxicology, and biomedical science, but most cannot be banked "ready to use" as they...
4.
Gao Y, Bissoyi A, Kinney N, Whale T, Guo Q, Gibson M
Chem Commun (Camb)
. 2023 Jul;
59(59):9086-9089.
PMID: 37401839
Spheroids mimic 3-D tissue niches better than standard cell cultures. Cryopreserving spheroids, however, remains challenging as conventional cryoprotectants do not mitigate all damage mechanisms. Here chemically-programmed extracellular ice nucleation is...
5.
Judge N, Georgiou P, Bissoyi A, Ahmad A, Heise A, Gibson M
Biomacromolecules
. 2023 Jun;
24(6):2459-2468.
PMID: 37303170
Ice-binding proteins (IBPs) from extremophile organisms can modulate ice formation and growth. There are many (bio)technological applications of IBPs, from cryopreservation to mitigating freeze-thaw damage in concrete to frozen food...
6.
Bissoyi A, Tomas R, Gao Y, Guo Q, Gibson M
ACS Appl Mater Interfaces
. 2023 Jan;
15(2):2630-2638.
PMID: 36621888
Spheroids are a powerful tool for basic research and to reduce or replace in vivo (animal) studies but are not routinely banked nor shared. Here, we report the successful cryopreservation...
7.
Georgiou P, Kinney N, Kontopoulou I, Baker A, Hindmarsh S, Bissoyi A, et al.
Biomacromolecules
. 2022 Nov;
23(12):5285-5296.
PMID: 36441868
Ice binding proteins (IBP) have evolved to limit the growth of ice but also to promote ice formation by ice-nucleating proteins (INPs). IBPs, which modulate these seemingly distinct processes, often...
8.
Forbes J, Bissoyi A, Eickhoff L, Reicher N, Hansen T, Bon C, et al.
Nat Commun
. 2022 Aug;
13(1):5019.
PMID: 36028506
Bacterial ice nucleation proteins (INPs) can cause frost damage to plants by nucleating ice formation at high sub-zero temperatures. Modeling of Pseudomonas borealis INP by AlphaFold suggests that the central...
9.
Tomas R, Bissoyi A, Congdon T, Gibson M
Biomacromolecules
. 2022 Aug;
23(9):3948-3959.
PMID: 35972897
Cell monolayers underpin the discovery and screening of new drugs and allow for fundamental studies of cell biology and disease. However, current cryopreservation technologies do not allow cells to be...
10.
Tripathi S, Kumar R, Bissoyi A, Rizvi S
Rejuvenation Res
. 2022 Mar;
25(2):70-78.
PMID: 35316094
Caloric restriction (CR) is the most effective intervention for extending the life span of vertebrate and invertebrate aging models. Calorie restriction mimetics (CRMs), which are synthetic or natural chemicals that...