Ajit S Dhaunchak
Overview
Explore the profile of Ajit S Dhaunchak including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
169
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0
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Recent Articles
1.
de Faria Jr O, Dhaunchak A, Kamen Y, Roth A, Kuhlmann T, Colman D, et al.
Sci Rep
. 2019 Mar;
9(1):3606.
PMID: 30837646
Oligodendrocyte precursor cells (OPCs) differentiate during postnatal development into myelin-forming oligodendrocytes, in a process distinguished by substantial changes in morphology and the onset of myelin gene expression. A mammalian-specific CNS...
2.
Belkaid W, Thostrup P, Yam P, Juzwik C, Ruthazer E, Dhaunchak A, et al.
BMC Biotechnol
. 2013 Oct;
13:86.
PMID: 24119185
Background: Normal development and the response to injury both require cell growth, migration and morphological remodeling, guided by a complex local landscape of permissive and inhibitory cues. A standard approach...
3.
de Faria Jr O, Moore C, Kennedy T, Antel J, Bar-Or A, Dhaunchak A
Front Genet
. 2013 Jan;
3:311.
PMID: 23346094
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous system (CNS) demyelination and axonal degeneration. Although the cause of MS is still unknown, it is widely accepted...
4.
Gopalakrishnan G, Awasthi A, Belkaid W, de Faria Jr O, Liazoghli D, Colman D, et al.
J Neurosci Res
. 2013 Jan;
91(3):321-34.
PMID: 23325434
To understand the molecular anatomy of myelin membranes, we performed a large-scale, liquid chromatography-coupled tandem mass spectrometry (LC-MS/MS)-based lipidome and proteome screen on freshly purified human and murine myelin fractions....
5.
Reines A, Bernier L, McAdam R, Belkaid W, Shan W, Koch A, et al.
J Neurosci
. 2012 May;
32(18):6323-34.
PMID: 22553038
Classical cadherins, which are adhesion molecules functioning at the CNS synapse, are synthesized as adhesively inactive precursor proteins in the endoplasmic reticulum (ER). Signal sequence and prodomain cleavage in the...
6.
de Faria Jr O, Cui Q, Bin J, Bull S, Kennedy T, Bar-Or A, et al.
Front Genet
. 2012 Apr;
3:46.
PMID: 22470405
MicroRNAs (miRs) regulate diverse molecular and cellular processes including oligodendrocyte (OL) precursor cell (OPC) proliferation and differentiation in rodents. However, the role of miRs in human OPCs is poorly understood....
7.
Dhaunchak A, Huang J, de Faria Junior O, Roth A, Pedraza L, Antel J, et al.
Glia
. 2010 Sep;
58(16):1949-60.
PMID: 20830807
Compact myelin, the paranode, and the juxtaparanode are discrete domains that are formed on myelinated axons. In humans, neurological disorders associated with loss of myelin, including Multiple Sclerosis, often also...