Ajit G Chande
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Explore the profile of Ajit G Chande including associated specialties, affiliations and a list of published articles.
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12
Citations
156
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Recent Articles
1.
Kumari S, Bodhale N, Sarode A, Jha M, Bhadange S, Pandey S, et al.
Int Immunopharmacol
. 2024 May;
134:112100.
PMID: 38728877
The parasite Leishmania resides as amastigotes within the macrophage parasitophorous vacuoles inflicting the disease Leishmaniasis. Leishmania selectively modulates mitogen-activated protein kinase (MAPK) phosphorylation subverting CD40-triggered anti-leishmanial functions of macrophages. The...
2.
Chande A, Siddiqui Z, Midha M, Sirohi V, Ravichandran S, Rao K
Sci Rep
. 2015 Aug;
5:13430.
PMID: 26303024
Upon infection, Mycobacterium tuberculosis (Mtb) deploys specialized secretion machinery to deliver virulent proteins with the capacity to modulate a variety of host-cellular pathways. Studies on the identification of intra-macrophage Mtb...
3.
Khan T, Srivastava N, Srivastava A, Sareen A, Mathur R, Chande A, et al.
J Immunol
. 2014 Sep;
193(7):3644-53.
PMID: 25187664
CD40 plays dual immunoregulatory roles in Leishmania major infection and tumor regression. The functional duality emerges from CD40-induced reciprocal p38MAPK and ERK-1/2 phosphorylations. Because phosphotyrosine-based signaling in hematopoietic cells is...
4.
Raina S, Chande A, Baba M, Mukhopadhyaya R
Virusdisease
. 2014 Jan;
25(1):101-6.
PMID: 24426316
Human immunodeficiency virus regulatory protein Rev (regulator of viral expression) is translated from a monocistronic transcript produced early in the viral replication cycle. Rev binds to the cis-acting, highly structured...
5.
Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, et al.
FASEB J
. 2014 Jan;
28(4):1756-68.
PMID: 24391131
Intramacrophage pathogen Leishmania donovani escapes host immune response by subverting Toll-like receptor (TLR) signaling, which is critically regulated by protein ubiquitination. In the present study, we identified tumor necrosis factor...
6.
Dhamne H, Chande A, Mukhopadhyaya R
Plasmid
. 2013 Dec;
71:1-7.
PMID: 24325878
Lentiviral vector (LV) mediated gene transfer holds great promise to develop stable cell lines for sustained transgene expression providing a valuable alternative to the conventional plasmid transfection based recombinant protein...
7.
Goel P, Tailor P, Chande A, Basu A, Mukhopadhyaya R
Virus Res
. 2013 Mar;
173(2):280-5.
PMID: 23454489
Human herpesvirus 6B (HHV-6B) primary infections occur in early childhood and establish a life-long latency in the most healthy adults. HHV-6B was detectable in the peripheral blood mononuclear cells (PBMC)...
8.
Chande A, Raina S, Dhamne H, Kamat R, Mukhopadhyaya R
Plasmid
. 2012 Nov;
69(1):90-5.
PMID: 23159456
Using the Indian Human immunodeficiency virus type 2 (HIV-2) isolate derived lentiviral vector (LV) system reported earlier, we have derived multiple differently configured transfer vectors. Among the features imparted, the...
9.
Sarma U, Sareen A, Maiti M, Kamat V, Sudan R, Pahari S, et al.
PLoS One
. 2012 Jul;
7(7):e39898.
PMID: 22815717
Depending on the strength of signal dose, CD40 receptor (CD40) controls ERK-1/2 and p38MAPK activation. At low signal dose, ERK-1/2 is maximally phosphorylated but p38MAPK is minimally phosphorylated; as the...
10.
Srivastav S, Kar S, Chande A, Mukhopadhyaya R, Das P
J Immunol
. 2012 Jun;
189(2):924-34.
PMID: 22685311
TLRs, which form an interface between mammalian host and microbe, play a key role in pathogen recognition and initiation of proinflammatory response thus stimulating antimicrobial activity and host survival. However,...