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Aixiao Liu

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Articles 9
Citations 424
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Recent Articles
1.
Li J, Ghiani C, Kim J, Liu A, Sandoval J, deVellis J, et al.
J Neurosci . 2008 Jun; 28(24):6118-27. PMID: 18550754
Oligodendrogliopathy, microglial infiltration, and lack of remyelination are detected in the brains of patients with multiple sclerosis and are accompanied by high levels of the transcription factor p53. In this...
2.
Liu A, Han Y, Li J, Sun D, Ouyang M, Plummer M, et al.
J Neurosci . 2007 Jul; 27(27):7339-43. PMID: 17611286
The identity of any cell type is determined by the specific pattern of gene expression. We show here that the ability of oligodendrocyte progenitors to acquire the identity of myelin-expressing...
3.
Shen S, Liu A, Li J, Wolubah C, Casaccia-Bonnefil P
Neurobiol Aging . 2006 Dec; 29(3):452-63. PMID: 17182153
In this study, we address the hypothesis that aging modifies the intrinsic properties of oligodendrocytes, the myelin-forming cells of the brain. According to our model, an "epigenetic memory" is stored...
4.
Liu A, Li J, Marin-Husstege M, Kageyama R, Fan Y, Gelinas C, et al.
EMBO J . 2006 Sep; 25(20):4833-42. PMID: 17006542
This study identifies novel mechanisms of Hes5 function in developmental myelination. We report here upregulation of myelin gene expression in Hes5-/- mice compared to wild-type siblings and downregulation in overexpressing...
5.
Liu A, Stadelmann C, Moscarello M, Bruck W, Sobel A, Mastronardi F, et al.
J Neurosci . 2005 Jan; 25(3):737-47. PMID: 15659612
Understanding the biological relevance of reexpression of developmental molecules in pathological conditions is crucial for the development of new therapies. In this study, we report the increased expression of stathmin,...
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Liu A, Muggironi M, Marin-Husstege M, Casaccia-Bonnefil P
Glia . 2003 Nov; 44(3):264-74. PMID: 14603467
Process outgrowth is crucial in oligodendrocyte (OL) development and myelination. It is well accepted that increased levels of proteins affecting the polymerization of cytoskeletal components promote branching. Interestingly, we have...
8.
Casaccia-Bonnefil P, Liu A
J Neurosci Res . 2003 Mar; 72(1):1-11. PMID: 12645074
No abstract available.
9.
Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P
J Neurosci . 2002 Nov; 22(23):10333-45. PMID: 12451133
Gene expression can be modulated by chromatin changes induced by histone acetylation and deacetylation. Acetylation of histone lysine residues by acetyltransferases is associated with transcriptionally active chromatin, whereas the removal...