Aisling Dunne
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Explore the profile of Aisling Dunne including associated specialties, affiliations and a list of published articles.
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56
Citations
2757
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Recent Articles
1.
ORourke S, Shanley L, Dunne A
Front Immunol
. 2024 Oct;
15:1457010.
PMID: 39380993
Nrf2 is a master transcriptional regulator of a number of genes involved in the adaptive response to oxidative stress. Among the genes upregulated by Nrf2, heme oxygenase-1 (HO-1) has received...
2.
Vozza E, Kelly A, Daly C, ORourke S, Carlile S, Morris B, et al.
Cell Death Discov
. 2024 Sep;
10(1):403.
PMID: 39271670
Staphylococcus aureus is an important human commensal which persistently colonizes up to 30% of the human population, predominantly within the nasal cavity. The commensal lifestyle of S. aureus is complex,...
3.
Vozza E, Daly C, ORourke S, Fitzgerald H, Dunne A, McLoughlin R
mBio
. 2023 Dec;
15(1):e0257123.
PMID: 38108639
is one of the leading causes of antimicrobial-resistant infections whose success as a pathogen is facilitated by its massive array of immune evasion tactics, including intracellular survival within critical immune...
4.
Shanley L, Mahon O, ORourke S, Neto N, Monaghan M, Kelly D, et al.
Acta Biomater
. 2023 Feb;
160:311-321.
PMID: 36754270
Since the recent observation that immune cells undergo metabolic reprogramming upon activation, there has been immense research in this area to not only understand the basis of such changes, but...
5.
Shanley L, Fitzgerald H, ORourke S, Dunne A
Exp Biol Med (Maywood)
. 2022 Dec;
247(24):2192-2200.
PMID: 36511089
Dysregulated metabolism has long been recognized as a feature of many metabolic disorders. However, recent studies demonstrating that metabolic reprogramming occurs in immune cells have led to a growing interest...
6.
Neto N, ORourke S, Zhang M, Fitzgerald H, Dunne A, Monaghan M
Elife
. 2022 Oct;
11.
PMID: 36254592
In this study, we utilise fluorescence lifetime imaging of NAD(P)H-based cellular autofluorescence as a non-invasive modality to classify two contrasting states of human macrophages by proxy of their governing metabolic...
7.
ORourke S, Neto N, Devilly E, Shanley L, Fitzgerald H, Monaghan M, et al.
Atherosclerosis
. 2022 Jun;
352:35-45.
PMID: 35667162
Background And Aims: Metabolic reprogramming of innate immune cells is emerging as a key player in the progression of a number of chronic diseases, including atherosclerosis, where high rates of...
8.
Fitzgerald H, ORourke S, Desmond E, Neto N, Monaghan M, Tosetto M, et al.
Antioxidants (Basel)
. 2022 Jan;
11(1).
PMID: 35052669
The extracellular parasite and causative agent of African sleeping sickness () has evolved a number of strategies to avoid immune detection in the host. One recently described mechanism involves the...
9.
Shanley L, Mahon O, Kelly D, Dunne A
Acta Biomater
. 2021 Mar;
133:208-221.
PMID: 33657453
Tissue healing and regeneration is a complex, choreographed, spatiotemporal process involving a plethora of cell types, the activity of which is stringently regulated in order for effective tissue repair to...
10.
Campbell N, Fitzgerald H, Dunne A
Nat Rev Immunol
. 2021 Jan;
21(7):411-425.
PMID: 33514947
Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of haem, is primarily considered an antioxidant, and has long been overlooked by immunologists. However, research over the past...