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Aishwariya Sharma

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Articles 13
Citations 231
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Recent Articles
1.
Meseguer-Ripolles J, Wang Y, Sorteberg A, Sharma A, Ding N, Lucendo-Villarin B, et al.
J Vis Exp . 2020 May; (159). PMID: 32449710
Liver disease is an escalating global health issue. While liver transplantation is an effective mode of therapy, patient mortality has increased due to shortages in donor organ availability. Organ scarcity...
2.
Dalal K, Ban F, Li H, Morin H, Roshan-Moniri M, Tam K, et al.
Cancer Lett . 2018 Aug; 437:35-43. PMID: 30165195
Prostate cancer (PCa) is a leading cause of death for men in North America. The androgen receptor (AR) - a hormone inducible transcription factor - drives expression of tumor promoting...
3.
Singh K, Munuganti R, Lallous N, Dalal K, Yoon J, Sharma A, et al.
Int J Mol Sci . 2018 Feb; 19(2). PMID: 29462880
Estrogen receptor-α positive (ERα⁺) breast cancers represent 75% of all invasive breast cancer cases, while de novo or acquired resistance to ER-directed therapy is also on the rise. Numerous factors...
4.
Dalal K, Che M, Que N, Sharma A, Yang R, Lallous N, et al.
Mol Cancer Ther . 2017 Aug; 16(10):2281-2291. PMID: 28775145
Human androgen receptor (AR) is a hormone-activated transcription factor that is an important drug target in the treatment of prostate cancer. Current small-molecule AR antagonists, such as enzalutamide, compete with...
5.
Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hassona M, et al.
J Biol Chem . 2017 Mar; 292(10):4359. PMID: 28283588
No abstract available.
6.
Tam K, Dalal K, Hsing M, Cheng C, Khosravi S, Yenki P, et al.
Oncotarget . 2016 Dec; 8(6):9617-9633. PMID: 28038451
The androgen receptor (AR) is a member of the nuclear receptor superfamily of transcription factors and is central to prostate cancer (PCa) progression. Ligand-activated AR engages androgen response elements (AREs)...
7.
Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hassona M, et al.
J Biol Chem . 2015 Oct; 290(43):25850. PMID: 26500294
No abstract available.
8.
Grewal N, Thornton G, Behzad H, Sharma A, Lu A, Zhang P, et al.
PLoS One . 2014 Dec; 9(12):e114214. PMID: 25502628
Objective: Clinical studies have suggested an association between dyslipidemia and tendon injuries or chronic tendon pain; the mechanisms underlying this association are not yet known. The objectives of this study...
9.
Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hessein M, et al.
J Biol Chem . 2014 Aug; 289(38):26417-26429. PMID: 25086042
The androgen receptor (AR) is a transcription factor that has a pivotal role in the occurrence and progression of prostate cancer. The AR is activated by androgens that bind to...
10.
Behzad H, Sharma A, Mousavizadeh R, Lu A, Scott A
Arthritis Res Ther . 2014 Feb; 15(6):R184. PMID: 24517261
Introduction: We have previously found an increased mast cell density in tendon biopsies from patients with patellar tendinopathy compared to controls. This study examined the influence of mast cells on...