Marco Demaria
Overview
Explore the profile of Marco Demaria including associated specialties, affiliations and a list of published articles.
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91
Citations
11089
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Recent Articles
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Short E, Huckstepp R, Alavian K, Amoaku W, Barber T, van Beek E, et al.
Geroscience
. 2025 Feb;
PMID: 39982667
No abstract available.
3.
Nehme J, Maassen S, Bravaccini S, Zanoni M, Gianni C, De Giorgi U, et al.
EMBO J
. 2025 Feb;
PMID: 39930269
Breast cancer is a leading cause of mortality worldwide. Pharmacological inhibitors of cyclin-dependent kinases (CDK) 4 and 6 (CDK4/6i) inhibit breast cancer growth by inducing a senescent-like state. However, the...
4.
Altulea A, Rutten M, Verdijk L, Demaria M
Geroscience
. 2024 Aug;
PMID: 39129051
The human lifespan is influenced by various factors, with physical activity being a significant contributor. Despite the clear benefit of exercise on health and longevity, the association between different types...
5.
Ogrodnik M, Carlos Acosta J, Adams P, dAdda di Fagagna F, Baker D, Bishop C, et al.
Cell
. 2024 Aug;
187(16):4150-4175.
PMID: 39121846
Cellular senescence is a cell fate triggered in response to stress and is characterized by stable cell-cycle arrest and a hypersecretory state. It has diverse biological roles, ranging from tissue...
6.
Nehme J, Mesilmany L, Varela-Eirin M, Brandenburg S, Altulea A, Lin Y, et al.
Nat Aging
. 2024 May;
4(6):771-782.
PMID: 38724734
Excessive amounts of reactive oxygen species (ROS) lead to macromolecular damage and high levels of cell death with consequent pathological sequelae. We hypothesized that switching cell death to a tissue...
7.
Wang B, Han J, Elisseeff J, Demaria M
Nat Rev Mol Cell Biol
. 2024 Apr;
25(12):958-978.
PMID: 38654098
Cellular senescence is a state of terminal growth arrest associated with the upregulation of different cell cycle inhibitors, mainly p16 and p21, structural and metabolic alterations, chronic DNA damage responses,...
8.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, et al.
STAR Protoc
. 2024 Mar;
5(1):102929.
PMID: 38460134
Identification and isolation of senescent cells is challenging, rendering their detailed analysis an unmet need. We describe a precise one-step protocol to fluorescently label senescent cells, for flow cytometry and...
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Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, et al.
Mol Cell
. 2023 Oct;
83(19):3558-3573.e7.
PMID: 37802028
Cellular senescence is a stress-response mechanism implicated in various physiological processes, diseases, and aging. Current detection approaches have partially addressed the issue of senescent cell identification in clinical specimens. Effective...