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Aijun Shen

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Articles 52
Citations 843
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Recent Articles
11.
Wei L, Cao Y, Zhang K, Xu Y, Zhou X, Meng J, et al.
Front Neurol . 2021 Jul; 12:652757. PMID: 34220671
Accurate prediction of the progression to severe stroke in initially diagnosed nonsevere patients with acute-subacute anterior circulation nonlacuna ischemic infarction (ASACNLII) is important in making clinical decision. This study aimed...
12.
Han Y, Liu Y, Ma X, Shen A, Liu Y, Weeranoppanant N, et al.
Biomaterials . 2021 May; 274:120849. PMID: 34022739
Chemotherapy-induced neutropenia, a symptom of neutrophil depletion, makes cancer patients highly susceptible to invasive fungal infection with substantial morbidity and mortality. To address the cryptococcal brain infection in this condition,...
13.
Li Z, Cheng S, Lin Q, Cao W, Yang J, Zhang M, et al.
Nat Commun . 2021 May; 12(1):2869. PMID: 34001877
Single-cell analysis is critical to revealing cell-to-cell heterogeneity that would otherwise be lost in ensemble analysis. Detailed lipidome characterization for single cells is still far from mature, especially when considering...
14.
Lv Q, Wang G, Zhang Y, Shen A, Tang J, Sun Y, et al.
J Exp Clin Cancer Res . 2021 Feb; 40(1):76. PMID: 33618745
Background: Accumulating evidence has revealed that circular RNAs (circRNAs), as novel noncoding RNAs, play critical roles in carcinogenesis and tumor progression. However, the functions and molecular mechanisms of circRNAs in...
15.
Chen J, Li Y, Zhang J, Zhang M, Wei A, Liu H, et al.
Eur J Med Chem . 2020 Oct; 209:112868. PMID: 33077265
According to the binding mode of ABBV-744 with bromodomains and the cape space of HDAC, the novel selective HDAC/BRD4 dual inhibitors were designed and synthesized by the pharmacophore fusion strategy....
16.
Han C, Liu Z, Zhang Y, Shen A, Dong C, Zhang A, et al.
Nat Immunol . 2020 Sep; 21(11):1470. PMID: 32939095
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
17.
Deng S, Sun Z, Qiao J, Liang Y, Liu L, Dong C, et al.
JCI Insight . 2020 Apr; 5(7). PMID: 32271164
The lack of sufficient functional tumor-infiltrating lymphocytes in the tumor microenvironment (TME) is one of the primary indications for the poor prognosis of patients with cancer. In this study, we...
18.
Wen H, Dong H, Liu J, Shen A, Li Y, Shi D
J Mater Chem B . 2020 Apr; 4(48):7859-7869. PMID: 32263776
Intelligent nanoparticles are capable of prolonged blood circulation without leakage of the payload and fast drug release upon exposure to environmental stimuli, such as redox stimuli, and therefore are highly...
19.
Wen Y, Dong H, Li Y, Shen A, Li Y
J Mater Chem B . 2020 Apr; 4(4):743-751. PMID: 32262955
Biomineralization of a rare earth ion (Gd) is first employed to assemble bovine serum albumin (BSA) into sub-50 nm nanoparticles (Gd@BSA) for theranostic applications, via a straightforward and reproducible strategy....
20.
Han C, Liu Z, Zhang Y, Shen A, Dong C, Zhang A, et al.
Nat Immunol . 2020 Apr; 21(5):546-554. PMID: 32231300
High-dose radiation activates caspases in tumor cells to produce abundant DNA fragments for DNA sensing in antigen-presenting cells, but the intrinsic DNA sensing in tumor cells after radiation is rather...