Aihong Kim
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Explore the profile of Aihong Kim including associated specialties, affiliations and a list of published articles.
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11
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8
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Recent Articles
1.
Kim A, Hong J
Nucleosides Nucleotides Nucleic Acids
. 2008 Jan;
27(2):121-30.
PMID: 18205067
This paper reports a new method for synthesizing an acyclic version of 6 '-methylene and 6 '(alpha)-methylated carbovir analogues. The introduction of a methylene group to the requisite 6 '-position...
2.
Kim A, Hong J
Nucleosides Nucleotides Nucleic Acids
. 2007 Apr;
26(3):291-302.
PMID: 17454738
This article reports the novel synthesis of substituted apiosyl nucleosides. The key apiosyl intermediate 9 was constructed by sequential ozonolysis, reductions, and acetylation from the ester derivative 6. The nucleosides...
3.
Kim A, Hong J
Eur J Med Chem
. 2006 Dec;
42(4):487-93.
PMID: 17188402
A series of novel fluorocyclopropyl nucleosides were synthesized starting from acetol using the Simmons-Smith reaction as a key reaction. All the nucleosides synthesized were assayed against several viruses. Among the...
4.
Kim A, Hong J, Oh C
Nucleosides Nucleotides Nucleic Acids
. 2006 Oct;
25(12):1399-406.
PMID: 17067961
A simple synthetic route for novel acyclic phosphonate nucleosides is described. The characteristic cyclopropyl moiety 8 was constructed employing the Simmons-Smith reaction as key step starting from simple acyclic 2-butene-1,4-diol....
5.
Kim A, Hong J
Nucleosides Nucleotides Nucleic Acids
. 2006 Aug;
25(8):941-50.
PMID: 16901824
This article describes a very simple route for synthesizing a novel 5'-norcarboacyclic nucleotides. The condensation of the mesylates 17 and 18 with the natural nucleosidic bases (A,U,T,C) under standard nucleophilic...
6.
Kim A, Hong J
Nucleosides Nucleotides Nucleic Acids
. 2006 Jan;
25(1):1-8.
PMID: 16440980
A very simple synthetic route for novel cyclopentene phosphonate nucleosides is described. The characteristic cyclopentene moiety 6 was constructed via a ring-closing metathesis of divinyl 5, which could be readily...
7.
Kim A, Hong J
Arch Pharm (Weinheim)
. 2005 Nov;
338(11):522-7.
PMID: 16281312
A very simple route for synthesizing a novel carboacyclic version of 5 cent-noraristeromycin is described. Condensation of the mesylates 9 and 23 with the natural nucleosidic bases (A, U, T,...
8.
Kim A, Hong J
Arch Pharm (Weinheim)
. 2005 Nov;
338(11):528-33.
PMID: 16281311
This paper describes a very simple synthesis route of novel acyclic nucleosides and phosphonic acid nucleosides. The condensation of the mesylates 6 and 17 with the natural nucleosidic bases (A,...
9.
Kim A, Hong J
Arch Pharm Res
. 2005 Nov;
28(10):1105-10.
PMID: 16276962
Novel anomeric branched carbocyclic nucleosides were synthesized from 1,3-dihydroxy acetone. 4'-Hydroxymethyl was installed by [3,3]-sigmatropic rearrangement reaction and 1'-methyl group was introduced by carbonyl addition of methylmagnesium bromide. The coupling...
10.
Kim A, Hong J
Nucleosides Nucleotides Nucleic Acids
. 2005 Feb;
24(1):63-72.
PMID: 15715199
This article reports the synthesis of novel 2',3',4'-trimethyl branched carbocyclic nucleosides. The introduction of a methyl group in the 2' and 3'-position was accomplished by sequential Horner-Wadsworth-Emmons reaction and isopropenyl...